Altering the landscape of viruses and bionanoparticles
Altering the landscape of viruses and bionanoparticles
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DOI：
10.1039/c1ob05700f
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发表时间：
2011-01-01
影响因子：
3.2
通讯作者：
Wang, Qian
中科院分区：
文献类型：
--
作者：
Lee, L. Andrew;Huong Giang Nguyen;Wang, Qian
近年来，基于蛋白质的纳米颗粒或生物纳米颗粒（BNP）已被用作主要构建块，以产生用于广泛应用的华丽纳米材料。在过去的50年中，许多BNP已经被化学修饰或遗传工程化以用作智能药物/基因递送载体、先进的疫苗载体和用于无机、金属和半导体沉积的隔离反应容器。这些研究为这些简单但高度坚固的纳米建筑材料的扩展能力提供了宝贵的见解。在这里，我们强调了一些最近的进展，在化学修饰的BNPs，并希望在不久的将来启发许多新材料的开发。
In recent years, protein-based nanoparticles or bionanoparticles (BNPs), have been used as primary building blocks to generate ornate nanomaterials for a wide-range of applications. Over the past fifty years, numerous BNPs have been chemically modified or genetically engineered to function as smart drug/gene delivery vehicles, advanced vaccine vehicles, and isolated reaction vessels for inorganic, metallic, and semi-conductive depositions. These studies have contributed invaluable insights to the expansive capabilities of these simple, yet highly robust, nanosized building materials. Here we highlight some of the recent progress in the chemical modifications of BNPs and hopefully inspire the development of many new materials in the near future.