Post-stroke depression among stroke survivors attending two hospitals in Kampala Uganda

Post-stroke depression among stroke survivors attending two hospitals in Kampala Uganda
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DOI:
10.4314/ahs.v15i4.22
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发表时间:
2015-01-01
影响因子:
1
通讯作者:
Katabira, Elly
Katabira, Elly
中科院分区:
医学4区
文献类型:
--
作者:
Gyagenda, Joseph Ogavu;Ddumba, Edward;Katabira, Elly

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背景:世界范围内卒中负担正在迅速增加。在乌干达中风幸存者中,中风后抑郁(PSD)的数据缺乏,尽管其他地方报道的PSD患病率很高。方法:在一项横断面研究中,我们用标准化问卷评估确诊首次中风的成年参与者。采用患者健康问卷-9对非失语患者进行抑郁评估,对失语患者采用失语抑郁评定量表。单变量和多变量分析描述了与PSD的关系。结果:卒中患者女性43例(58.9%),男性30例(41.1%)。58人(79.5%)患有缺血性中风,12人(16.4%)患有失语症。ptsd在研究参与者中的患病率为31.5%。在中风发作后6个月内评估的患者中,PSD较高。PSD与Barthel日常生活活动指数(BIADL)总分呈显著正相关;p = 0.001。人口学特征与PSD之间无显著相关性。结论:脑卒中后未被认识到的抑郁患病率较高。卒中后抑郁与患者无法进行日常生活活动密切相关。目前迫切需要对脑卒中幸存者进行脑卒中后抑郁的筛查和管理。
Background: The burden of stroke worldwide is increasing rapidly. There is paucity of data on post-stroke depression (PSD) among stroke survivors in Uganda, despite the high prevalence of PSD reported elsewhere.Methods: In a cross-sectional study, we assessed adult participants with confirmed first stroke with a standardized questionnaire. The Patient Health Questionnaire-9 was used to assess for depression among non-aphasic patients while the Aphasic Depression Rating Scale was administered to aphasic patients. Univariable and multivariable analyses performed to describe associations with PSD.Results: Forty three females (58.9%) and 30 males (41.1%) who had a stroke participated. Fifty eight (79.5%) had ischemic strokes and 12 participants (16.4%) were aphasic. The prevalence of PSD among the study participants was 31.5%. PSD was higher among patients assessed within 6 months after the onset of stroke. PSD was strongly associated with the total Barthel index of activities of daily living (BIADL) score; p=0.001. There was no significant association between demographic characteristics and PSD.Conclusion: There is a high prevalence of unrecognized post-stroke depression. Post-stroke depression was strongly associated with the patient's inability to undertake activities of daily life. There is urgent need for integration of screening for and management of post-stroke depression among stroke survivors.