Risk factors for coronary, aortic arch and carotid calcification; The Rotterdam Study
Risk factors for coronary, aortic arch and carotid calcification; The Rotterdam Study
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DOI：
10.1038/jhh.2009.42
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发表时间：
2010-02-01
影响因子：
2.7
通讯作者：
Witteman, J. C. M.
中科院分区：
文献类型：
--
作者：
Odink, A. E.;van der Lugt, A.;Witteman, J. C. M.
本研究旨在通过多层螺旋CT（MSCT）评估心血管危险因素与冠状动脉、主动脉弓和颈动脉钙化的相关性。本研究纳入鹿特丹研究，这是一项在55岁及以上受试者中开展的基于人群的研究。从2003年10月至2004年12月，受试者被邀请接受MSCT扫描。根据Agatston评分对冠状动脉、主动脉弓和颈动脉钙化进行量化。对前1003例受试者进行了分析。年龄和目前吸烟是动脉钙化最强的独立危险因素。女性年龄的优势比（OR）为1.1（P
This study was performed to examine the association of cardiovascular risk factors with calcification in the coronary arteries, aortic arch and carotid arteries, assessed by multislice computed tomography (MSCT). This study was embedded in the Rotterdam Study, a population-based study in subjects aged 55 years and over. From October 2003 until December 2004, subjects were invited to undergo a MSCT scan. Coronary, aortic arch and carotid calcification were quantified according to the Agatston score. Analyses were performed in the first 1003 subjects. Age and current smoking were the strongest independent risk factors for arterial calcification. The odds ratio (OR) for age in women, irrespective of the vessel bed, was 1.1 (P