MEIOTIC STUDIES AND SYNAPTONEMAL COMPLEX-ANALYSIS IN 2 INFERTILE MALES WITH A 13/14 BALANCED TRANSLOCATION
MEIOTIC STUDIES AND SYNAPTONEMAL COMPLEX-ANALYSIS IN 2 INFERTILE MALES WITH A 13/14 BALANCED TRANSLOCATION
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DOI：
10.1007/bf00272992
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发表时间：
1984-01-01
期刊：
影响因子：
5.3
通讯作者：
EGOZCUE, J
中科院分区：
文献类型：
--
作者：
TEMPLADO, C;VIDAL, F;EGOZCUE, J
对2例13/14易位不育男性进行了减数分裂和联会复合体的光镜和电镜观察。正如预期的那样，在常规减数分裂制备中，所有的中期I图都含有一个三价链。联会复合体的研究表明，典型的三价图像与不完全配对的近端着丝粒元件的顺式配置。文献回顾表明，这些患者的生育能力是相当可变的。所有患者的交叉数均略有减少（平均46.6）。EM研究发现，顺式配对似乎没有预后价值。
Meiotic and synaptonemal complex studies by light microscopy and EM were carried out in 2 infertile males with a balance 13/14 translocation. As expected, all metaphase I figures in conventional meiotic preparations contained a chain trivalent. Synaptonemal complex studies showed typical trivalent images with incomplete pairing of the acrocentric elements in the cis configuration. A review of the literature shows that the fertility of these patients is quite variable. All of them show a slightly reduced number of chiasmata (mean 46.6). Pairing in cis, as detected by EM studies, does not seem to have a prognostic value.