Comparison of Three-Dimensional T1-Weighted Magnetic Resonance and Contrast-Enhanced Ultrasound Plaque Images for Severe Stenosis of the Cervical Carotid Artery
Comparison of Three-Dimensional T1-Weighted Magnetic Resonance and Contrast-Enhanced Ultrasound Plaque Images for Severe Stenosis of the Cervical Carotid Artery
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DOI：
10.1016/j.jstrokecerebrovasdis.2017.06.029
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发表时间：
2017-09-01
影响因子：
2.5
通讯作者：
Ogasawara, Kuniaki
中科院分区：
文献类型：
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作者：
Shimada, Yasuyoshi;Oikawa, Kohki;Ogasawara, Kuniaki
背景和目的：磁共振（MR）和对比增强超声分别评估颈动脉斑块的特征和新生血管形成。本研究的目的是阐明颈动脉重度狭窄（≥ 70%）时，对比增强超声斑块成像与三维（3D）快速自旋回波（FSE）T1加权MR斑块成像（WI）的结果之间的关系。方法：53例患者均行三维快速自旋回波T1-WI及超声造影检查。对于每个患者，通过将平均颈内动脉斑块信号强度除以胸锁乳突肌信号强度来计算MR上的平均对比度（CRMR）;从对比增强的超声数据获得斑块内和管腔时间-强度曲线上的最大增强强度，计算斑块内曲线最大强度与管腔曲线最大强度的比值，定义为对比效应（CEUS）。结果：线性相关（r =.702; P
Background and Purpose: Magnetic resonance (MR) and contrast-enhanced ultrasound assess characteristics and neovascularization, respectively, of the carotid plaque. The purpose of the present study was to clarify how findings of contrast-enhanced ultrasound plaque imaging are related to those of 3-dimensional (3D) fast spin echo (FSE) T1-weighted MR plaque imaging (WI) in severe stenosis (>= 70%) of the cervical carotid artery. Methods: Fifty-three patients underwent 3D FSE T1-WI and contrast-enhanced ultrasound. For each patient, the averaged contrast ratio on MR (CRMR) was calculated by dividing the averaged internal carotid artery plaque signal intensity by the sternocleidomastoid muscle signal intensity; maximally enhanced intensities on the intraplaque and lumen time-intensity curves were obtained from contrast-enhanced ultrasound data, and the ratio of the maximal intensity of the intraplaque curve to that of the lumen curve was calculated and defined as contrast effect (CEUS). Results: A linear correlation (r =.702; P