Recent advances in the study of age-related hearing loss: a mini-review.
Recent advances in the study of age-related hearing loss: a mini-review.
复制标题
与年龄相关的听力损失研究的最新进展：小型审查。
作者：
Kidd Iii AR;Bao J
Hearing loss is a common age-associated affliction that can result from the loss of hair cells and spiral ganglion neurons (SGNs) in the cochlea. Although hair cells and SGNs are typically lost in the same cochlea, recent analysis suggests that they can occur independently, via unique mechanisms. Research has identified both environmental and genetic factors that contribute to degeneration of cochlear cells. Additionally, molecular analysis has identified multiple cell signaling mechanisms that likely contribute to pathological changes that result in hearing deficiencies. These analyses should serve as useful primers for future work, including genomic and proteomic analysis, to elucidate the mechanisms driving cell loss in the aging cochlea. Significant progress in this field has occurred in the past decade. As our understanding of aging-induced cochlear changes continues to improve, our ability to offer medical intervention will surely benefit the growing elderly population.
登录
查看更多内容
影响因子：
4.2
作者：
Fairfield, DA;Lomax, MI;Altschuler, RA
通讯作者：
Altschuler, RA
影响因子：
7.4
作者：
Coling, DE;Yu, KCY;Lalwani, AK
通讯作者：
Lalwani, AK
周围神经元中Ca2+稳态的年龄依赖性变化：对功能变化的影响。
影响因子：
7.8
作者：
Buchholz, John N;Behringer, Erik J;Pottorf, William J;Pearce, William J;Vanterpool, Conwin K
通讯作者：
Vanterpool, Conwin K
影响因子：
4.2
作者：
Jin D;Ohlemiller KK;Lei D;Dong E;Role L;Ryugo DK;Bao J
通讯作者：
Bao J
影响因子：
2.8
作者：
Gates, GA;Schmid, P;D'Agostino, R
通讯作者：
D'Agostino, R