Improved Cole parameter extraction based on the least absolute deviation method
Improved Cole parameter extraction based on the least absolute deviation method
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DOI：
10.1088/0967-3334/34/10/1239
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发表时间：
2013-10
影响因子：
3.2
通讯作者：
Yuxiang Yang;Wenwen Ni;Q. Sun;He Wen;Zhaosheng Teng
中科院分区：
文献类型：
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作者：
Yuxiang Yang;Wenwen Ni;Q. Sun;He Wen;Zhaosheng Teng
Cole函数在生物阻抗谱（BIS）中有着广泛的应用。将测量的BIS数据拟合到模型上，然后提取Cole参数（R0, R∞，α和τ）是一种常见的做法。从测量的BIS数据中准确提取Cole参数对评估生物组织的生理或病理状态具有重要意义。传统的基于最小二乘（LS）曲线拟合的Cole参数提取方法往往对噪声或异常值敏感，变得不鲁棒。提出了一种改进的基于最小绝对偏差（LAD）法的Cole参数提取方法。进行了全面的仿真实验，比较了存在异常点、随机噪声和两种干扰情况下LAD方法与LS方法的性能。所提出的LAD方法在各种情况下都表现出更好的鲁棒性，这表明LAD方法具有对异常值和噪声的鲁棒性，值得作为LS方法的改进替代方案进行Cole参数提取。
The Cole function is widely used in bioimpedance spectroscopy (BIS) applications. Fitting the measured BIS data onto the model and then extracting the Cole parameters (R0, R∞, α and τ) is a common practice. Accurate extraction of the Cole parameters from the measured BIS data has great significance for evaluating the physiological or pathological status of biological tissue. The traditional least-squares (LS)-based curve fitting method for Cole parameter extraction is often sensitive to noise or outliers and becomes non-robust. This paper proposes an improved Cole parameter extraction based on the least absolute deviation (LAD) method. Comprehensive simulation experiments are carried out and the performances of the LAD method are compared with those of the LS method under the conditions of outliers, random noises and both disturbances. The proposed LAD method exhibits much better robustness under all circumstances, which demonstrates that the LAD method is deserving as an improved alternative to the LS method for Cole parameter extraction for its robustness to outliers and noises.