Tracking of body size from birth to late adolescence:: Contributions of birth length, birth weight, duration of gestation, parents' body size, and twinship
Tracking of body size from birth to late adolescence:: Contributions of birth length, birth weight, duration of gestation, parents' body size, and twinship
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DOI：
10.1093/aje/154.1.21
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发表时间：
2001-07-01
影响因子：
5
通讯作者：
Rose, RJ
中科院分区：
文献类型：
--
作者：
Pietiläinen, KH;Kaprio, J;Rose, RJ
出生体重与成人体重指数（BMI）呈正相关，但很少考虑出生长度，妊娠期或父母的体型。作者研究了对出生身长和体重的跟踪，根据胎龄进行了调整，直到青春期后期，特别是父母的身高和BMI。纵向信息从芬兰双胞胎青少年（出生队列1975-1979年）的全国代表性样本和他们的父母通过邮寄问卷收集时，双胞胎16岁（n = 4，376; 2，062男，2，314女）和18岁（n = 3，917; 1，742男，2，175女）。从出生到青春期后期，双胞胎的身体尺寸表现出明显的跟踪，这在很大程度上受到父母身体尺寸的影响。青春期的身高是由出生时的身高和体重以及父母的身高预测的，而BMI是由出生体重和父母的BMI预测的。一个特别高的风险超重被发现的平均长度，但在出生时体重高的主题。这些研究结果表明，子宫内时期对以后的身体大小有持久的影响，但这些影响是遗传还是环境的问题尚未解决。
Birth weight has correlated positively with adult body mass index (BMI), but rarely have birth length, duration of gestation, or parents' body size been taken into account. The authors examined tracking of birth length and weight, adjusted for gestational age, to late adolescence, with special reference to parents' height and BMI. Longitudinal information from a nationally representative sample of Finnish twin adolescents (birth cohorts 1975-1979) and their parents was collected via questionnaires mailed when the twins were aged 16 years (n = 4,376; 2,062 males, 2,314 females) and 18 years (n = 3,917; 1,742 males, 2,175 females). The twins showed significant tracking of body size from birth to late adolescence, which was greatly influenced by their parents' body size. Height in adolescence was predicted by length and weight at birth and by parents' height, whereas BMI was predicted by birth weight and parents' BMI. An especially high risk for overweight was found for subjects of average length but a high weight at birth. These findings suggest that the intrauterine period has enduring effects on later body size but leave unresolved whether these effects are genetic or environmental.