Associations between multivitamin supplement use and alcohol consumption before pregnancy: Pregnancy Risk Assessment Monitoring System, 2004 to 2008.
Associations between multivitamin supplement use and alcohol consumption before pregnancy: Pregnancy Risk Assessment Monitoring System, 2004 to 2008.
复制标题
多种维生素补充剂的使用与怀孕前饮酒之间的关联：怀孕风险评估监测系统，2004 年至 2008 年。
DOI：
10.1111/acer.12120
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Chambers,ChristinaD
中科院分区：
文献类型：
--
作者：
Weiss,LaurenA;Chambers,ChristinaD
研究背景大约50%到70%的育龄妇女饮酒，高达23%的孕妇有不同程度的产前酒精暴露。方法利用2004年至2008年怀孕风险评估监测系统的数据，111,644名完成了与围产期酒精使用和复合维生素补充剂使用相关的问题的妇女被纳入研究。这项研究探讨了妊娠期饮酒和复合维生素补充剂使用之间的关系。结果在受孕期内，饮酒(≤3次，OR=0.76；4~6次/wk，OR=0.60；7~13次/wk，OR=0.49；≥14次/wk，OR=0.39)和酗酒(1次，OR=0.76；2~3次，OR=0.66)和酗酒(1次，OR=0.76；2~3次，OR=0.66；4~5倍，OR=0.56；≥=6倍，OR=0.50)与不饮酒者相比，服用复合维生素补充剂的可能性显著降低。结论本研究结果强调了围产期服用复合维生素补充剂的重要性，尤其是在饮酒育龄妇女中。
BackgroundApproximately 50 to 70% of childbearing‐aged women consume alcohol and up to 23% of pregnancies have some level of prenatal alcohol exposure.MethodsUsing data from the Pregnancy Risk Assessment Monitoring System from 2004 to 2008, 111,644 women who completed questions relating to periconceptional alcohol use and multivitamin supplement use were included in the study. This study explored associations between periconceptional alcohol use and multivitamin supplementation use. Weighted multivariable logistic regression was used to explore associations, adjusting for maternal education, maternal ethnicity, maternal age, household income, and parity.ResultsDuring the periconceptional period, a dose‐dependent association was found where women who consumed alcohol (≤3 drinks/wk, odds ratio [OR] = 0.76; 4 to 6 drinks/wk, OR = 0.60; 7 to 13 drinks/wk, OR = 0.49; ≥14 drinks/wk, OR = 0.39) and binged on alcohol (1 time, OR = 0.76; 2 to 3 times, OR = 0.66; 4 to 5 times, OR = 0.56; ≥6 times, OR = 0.50) were significantly less likely to take a multivitamin supplement compared with those that did not consume alcohol.ConclusionsThese findings emphasize the importance of periconceptional multivitamin supplement use, especially among alcohol‐consuming women of childbearing age.