Silver nanoparticles within vertically aligned multi-wall carbon nanotubes with open tips for antibacterial purposes
Silver nanoparticles within vertically aligned multi-wall carbon nanotubes with open tips for antibacterial purposes
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DOI：
10.1039/c0jm02395g
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发表时间：
2011-01-01
影响因子：
--
通讯作者：
Mohajerzadeh, S.
中科院分区：
文献类型：
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作者：
Akhavan, O.;Abdolahad, M.;Mohajerzadeh, S.
采用等离子体增强化学气相沉积法在镍/硅基底上以尖端生长模式制备了垂直排列的多壁碳纳米管（CNT）阵列。在对镍/碳纳米管进行包括氢化和酸洗的纯化过程中，含氧官能团大幅减少，并且通过去除镍颗粒在碳纳米管尖端形成了一个宽大的中空核。溶胶 - 凝胶银纳米粒子沉积在未纯化的镍/碳纳米管表面，同时它们也可嵌入去除镍后的碳纳米管的中空核内。与在稀硝酸溶液中银离子从银 - 镍/碳纳米管中释放相比，去除镍的银 - 碳纳米管中银离子的持久性证实了银纳米粒子有效地嵌入到去除镍的碳纳米管的中空核内。在黑暗环境下，去除镍的银 - 碳纳米管对大肠杆菌表现出很强的抗菌活性（与去除镍的碳纳米管和银 - 镍/碳纳米管相比，在120分钟内细菌的失活率分别为99.8±0.1%，而去除镍的碳纳米管和银 - 镍/碳纳米管的失活率分别为62±11%和47±18%），然而细菌甚至在未纯化的镍/碳纳米管阵列表面出现了一些增殖现象。基于细菌细胞膜通过直接接触机制破裂的情况，有人提出镍颗粒是细菌与碳纳米管阵列尖端有效接触的障碍。
Vertically aligned multi-wall carbon nanotube (CNT) arrays were fabricated in tip-growth mode on Ni/Si substrates using plasma enhanced chemical vapor deposition. In a purification process including hydrogenation and acid washing of the Ni/CNTs, the oxygen-containing functional groups were substantially reduced and a wide hollow core at the tip of the CNTs was formed by removing the Ni seeds. Sol-gel silver nanoparticles were deposited on the surface of the unpurified Ni/CNTs, while they could also be embedded within the hollow core of the Ni-removed CNTs. The persistency of the silver ions in the Ni-removed Ag-CNTs in comparison to the release of the silver ions from the Ag-Ni/CNTs in a dilute HNO3 solution confirmed the effective embedding of the Ag nanoparticles within the hollow core of the Ni-removed CNTs. The Ni-removed Ag-CNTs showed a strong antibacterial activity against Escherichia coli bacteria in the dark (inactivation of 99.8 +/- 0.1% of the bacteria as compared to the Ni-removed CNTs and the Ag-Ni/CNTs with 62 +/- 11 and 47 +/- 18% inactivation in 120 min), while the bacteria even exhibited some proliferation on the surface of the unpurified Ni/CNT arrays. In the context of cell membrane rupture of the bacteria through a direct contact mechanism, it was proposed that the Ni seeds acted as obstacles for an effective contact between the bacteria and the tips of the CNT arrays.