Brachial Artery Blood Flow Measurement: A Simple and Noninvasive Method to Evaluate the Need for Arteriovenous Fistula Repair
Brachial Artery Blood Flow Measurement: A Simple and Noninvasive Method to Evaluate the Need for Arteriovenous Fistula Repair
复制标题
DOI：
10.1002/dat.20565
复制
发表时间：
2011-05-01
影响因子：
--
通讯作者：
Mitarai, Tetsuya
中科院分区：
文献类型：
--
作者：
Ogawa, Tomonari;Matsumura, Osamu;Mitarai, Tetsuya
方法：对236例维持性血液透析患者的肱动脉血流检测结果与动静脉瘘修复及预后的关系进行研究。结果：经皮腔内血管成形术(PTA，n=161)患者的平均肱动脉血流量明显低于未治疗组(n=，250.3 m L/m in对656.7 m L/m in，p<；0.0001)。当使用ROC曲线分析平均肱动脉血流量与PTA需求之间的关系时，具有高敏感性(真阳性分数)和1特异性(假阳性分数)的最佳临界值为348.8毫升/分钟(ROC曲线下面积=0.814，真阳性分数=0.125，假阳性分数=0.87)。结论：350mL/分钟的肱动脉血流量减少与动静脉动静脉瘘修复的需要有关，提示这种简单、无创的方法可用于评估血管通路的通畅性和动静脉动静脉瘘的适应证。
OBJECTIVE: The objective of this study was to evaluate the utility of brachial artery blood flow measurement in assessing the need for arteriovenous fistula (AVF) repair.METHODS: In 236 hemodialysis patients, the relationships between the brachial artery blood flow measurement results and subsequent AVF repair and prognosis were investigated.RESULTS: Mean brachial artery blood flow was significantly lower in patients requiring percutaneous transluminal angioplasty (PTA; treatment group, n = 161) than in patients followed without any treatment (no treatment group, n = 64; 250.3 mL/min versus 656.7 mL/min, p < 0.0001). When the relationship between the mean brachial artery blood flow and PTA requirement was analyzed using the ROC curve, the optimal cut-off value with high sensitivity (true-positive fraction [TPF]) and 1-specificity (false-positive fraction [FPF]) was 348.8 mL/min (area under the ROC curve = 0.814, FPF = 0.125, TPF = 0.87).CONCLUSIONS: Decreased brachial artery blood flow of < 350 mL/min is associated with the need for subsequent AVF repair, suggesting that this simple and noninvasive method could be used to evaluate vascular access (VA) patency and indication for AVF repair.