Association of depression & health related quality of life with body composition in children and youth with obesity
Association of depression & health related quality of life with body composition in children and youth with obesity
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DOI：
10.1016/j.jad.2014.09.014
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发表时间：
2015-02-01
影响因子：
6.6
通讯作者：
Taylor, Valerie H.
中科院分区：
文献类型：
--
作者：
Morrison, Katherine M.;Shin, Sabina;Taylor, Valerie H.
背景：人们越来越认识到儿科人群中精神疾病和肥胖之间的关系。我们的目标是在临床环境中探索肥胖青少年抑郁症状和 HRQOL 的个体、生物学和家庭决定因素。方法：我们研究了 244 名 8-17 岁开始体重管理计划的青少年。使用流行病学研究中心儿童抑郁量表问卷评估抑郁症状，得分≥15或使用抗抑郁药物表明抑郁。使用PecISQL4.0检查HRQOL。我们考虑了年龄、性别、健康史、人体测量学、体脂、家庭健康和社会经济地位 (SES) 对抑郁症和 HRQOL 的影响。结果：抑郁症在该人群中很常见 (36.4%)。在多变量分析中，肥胖程度（体脂）可预测抑郁症 (OR 11(10-12)' p=0.05) 和低 HRQOL 评分 (# 0.63 (p < 0.001))。家庭 SES 是抑郁症的重要预测因子，但不是 HRQOL。与基于人群的研究相反，性别、年龄、青春期状态和抑郁症家族史并不能预测抑郁症状。局限性：由于这项研究包括寻求肥胖治疗的儿童和青少年，因此结果可能无法推广到肥胖青少年的一般人群。结论：抑郁症和低 HRQOL 在进入体重管理计划的青少年中很常见。肥胖程度可预测抑郁症状和低 HRQOL。该人群抑郁症的预测因子与所研究的非肥胖人群不同。重要的是要考虑这些特征，以帮助临床医生识别这些儿童。 (C) 2014 年爱思唯尔作者。版权所有
Background: There is an increasing recognition of the relationship between mental illness and obesity in the pediatric population. Our objective was to explore the individual, biological and family determinants of depressive symptoms and HRQOL in youth with obesity in a clinical setting.Methods: We studied 244 youth aged 8-17 years at the time of entry to a weight management program. Depressive symptoms were evaluated using the Center for Epidemiological Studies Depression Scale for Children questionnaire, with a score of >= 15 or antidepressant use indicating depression. HRQOL was examined using the PecIsQL4.0. We considered the influence of age, sex, health history, anthropometry, body fat, family health and socioeconomic status (SES) on depression and HRQOL.Results: Depression was common in this population (36.4%). In multivariate analysis, the extent of obesity (body fat) predicted both depression (OR 11(10-12)' p=0.05) and low HRQOL scores (# 0.63 (p < 0.001)). Family SES was an important predictor of depression but not of HRQOL. In contrast to population-based studies, sex, age, pubertal status and family history of depression did not predict depressive symptoms. Limitations: As this study included children and adolescents seeking obesRy treatment, results may not be generalizable to the general population of obese youth.Conclusions: Depression and low HRQOL are common in youth entering weight management programs. Extent of obesity predicted depressive symptoms and low HRQOL. Predictors of depression in this population differ from non obese populations studied. It is important to consider these characteristics to assist clinicians in identifying these children. (C) 2014 Elsevier By. All rights reserved