FACTORS AFFECTING OUTCOME OF SARCOIDOSIS - INFLUENCE OF RACE, EXTRATHORACIC INVOLVEMENT, AND INITIAL RADIOLOGIC LUNG LESIONS
FACTORS AFFECTING OUTCOME OF SARCOIDOSIS - INFLUENCE OF RACE, EXTRATHORACIC INVOLVEMENT, AND INITIAL RADIOLOGIC LUNG LESIONS
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DOI：
10.1111/j.1749-6632.1986.tb18537.x
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发表时间：
1986-06-06
影响因子：
5.2
通讯作者：
DELISSER, OG
中科院分区：
文献类型：
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作者：
ISRAEL, HL;KARLIN, P;DELISSER, OG
采用改良的ILO/UC命名法对152例2/3型疾病患者的胸部X线片进行了回顾性分析。平均观察9.3年后，71.7%的患者临床恢复，48.0%的患者影像学恢复。年龄：观察时间;纵隔淋巴结病; 53名白色和99名黑人患者的肺密度的特征（XYZ、PGR、STU）、大小、范围和灌注相似，仅在性别分布上有显著差异。白色患者临床恢复率（84.9%）高于黑人患者（64.7%）（p=. 05）。采用逐步Logistic回归分析影响临床恢复的因素。最初的X线特征与预后无关，只有种族和胸外疾病被证明具有显著的预测价值。临床恢复的概率估计为。894例白色患者的疾病仅限于胸部，697例白色胸外疾病患者。760例黑人患者没有和。454例黑人胸外结节病患者。恢复似乎与初始肺部反应的严重程度无关，但与影响胸外播散和肺损伤的种族相关因素有关。
Chest roentgenograms of 152 patients with type 2/3 disease observed 3 or more years were reviewed using modified ILO/UC nomenclature. After a mean length of observation of 9.3 years, clinical recovery was observed in 71.7% and radiologic recovery in 48.0% of the patients. Age; duration of observation; mediastinal adenopathy; and character (xyz, pgr, stu), size, extent, and profusion of pulmonary densities were similar in the 53 white and 99 black patients, who differed significantly only in sex distribution. White patients achieved clinical recovery (84.9%) more often than black patients (64.7%)(p=. 05). Factors influencing clinical recovery were analyzed by means of stepwise logistic linear regression. The initial roentgenographic features were unrelated to outcome; only race and extrathoracic disease proved to have significant predictive value. The probability of clinical recovery is estimated to be. 894 in white patients with disease limited to the chest,. 697 in white patients with extrathoracic disease, and. 760 in black patients without and. 454 in black patients with extrathoracic sarcoidosis. Recovery appears to be related not to the severity of the initial pulmonary reaction but to racially associated factors that influence extrathoracic dissemination as well as lung damage.