The systems biology markup language (SBML):: a medium for representation and exchange of biochemical network models

The systems biology markup language (SBML):: a medium for representation and exchange of biochemical network models
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DOI:
10.1093/bioinformatics/btg015
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发表时间:
2003-03-01
期刊:
影响因子:
5.8
通讯作者:
Wang, J
Wang, J
中科院分区:
生物学3区
文献类型:
--
作者:
Hucka, M;Finney, A;Wang, J

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动机:分子生物技术现在可以建立精心设计的系统模型,但系统生物学社区需要的信息标准,如果模型是共享的,评估和开发cooperatively.Results:我们总结了系统生物学标记语言(SBML)1级,一个免费的,开放的,基于XML的格式表示生化反应网络。SBML是一种独立于软件的语言,用于描述计算生物学许多领域的研究中常见的模型,包括细胞信号传导途径,代谢途径,基因调控等。
Motivation: Molecular biotechnology now makes it possible to build elaborate systems models, but the systems biology community needs information standards if models are to be shared, evaluated and developed cooperatively.Results: We summarize the Systems Biology Markup Language (SBML) Level 1, a free, open, XML-based format for representing biochemical reaction networks. SBML is a software-independent language for describing models common to research in many areas of computational biology, including cell signaling pathways, metabolic pathways, gene regulation, and others.