Bandage: interactive visualization of de novo genome assemblies.
Bandage: interactive visualization of de novo genome assemblies.
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DOI：
10.1093/bioinformatics/btv383
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发表时间：
2015-10-15
期刊：
影响因子：
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通讯作者：
Holt, Kathryn E
中科院分区：
文献类型：
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作者：
Wick, Ryan R;Schultz, Mark B;Holt, Kathryn E
unlabeled：尽管从头组装图包含组装的contigs（节点），但这些contigs（边）之间的连接对用户来说很难访问。绷带（一个生物信息学应用程序导航从头组装图很容易）是一个工具，用于可视化装配图与连接。用户可以放大图形的特定区域，并通过移动节点、添加标签、更改颜色和提取序列与之交互。BLAST搜索可以在绷带图形用户界面中执行，命中的结果将在图形中高亮显示。通过显示contigs之间的连接，绷带提供了新的可能性来分析从头组装，这是不可能通过单独研究contigs来实现的。可用性和实现：源代码和二进制文件可在https://github.com/rrwick/Bandage免费获得。绷带是用c++实现的，支持Linux、OS X和Windows。完整的功能列表和屏幕截图可在http://rrwick.github.io/Bandage.CONTACT: rrwick@gmail.comSUPPLEMENTARY获取信息：补充数据可在Bioinformatics在线获取。
UNLABELLED: Although de novo assembly graphs contain assembled contigs (nodes), the connections between those contigs (edges) are difficult for users to access. Bandage (a Bioinformatics Application for Navigating De novo Assembly Graphs Easily) is a tool for visualizing assembly graphs with connections. Users can zoom in to specific areas of the graph and interact with it by moving nodes, adding labels, changing colors and extracting sequences. BLAST searches can be performed within the Bandage graphical user interface and the hits are displayed as highlights in the graph. By displaying connections between contigs, Bandage presents new possibilities for analyzing de novo assemblies that are not possible through investigation of contigs alone.AVAILABILITY AND IMPLEMENTATION: Source code and binaries are freely available at https://github.com/rrwick/Bandage. Bandage is implemented in C++ and supported on Linux, OS X and Windows. A full feature list and screenshots are available at http://rrwick.github.io/Bandage.CONTACT: rrwick@gmail.comSUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.