High-resolution high-speed panoramic cardiac imaging system

High-resolution high-speed panoramic cardiac imaging system
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DOI:
10.1109/tbme.2007.912417
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发表时间:
2008-03-01
影响因子:
4.6
通讯作者:
Wikswo, John P.
Wikswo, John P.
中科院分区:
工程技术2区
文献类型:
--
作者:
Evertson, Dale W.;Holcomb, Mark R.;Wikswo, John P.

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本文介绍了一种由三台高速CCD摄像机组成的全景心脏成像系统,利用电压敏感荧光染料对兔心脏进行荧光成像。一个强大的,独特的机械系统,以适应三个摄像头,并适应未来的实验要求。一个统一的计算机接口被创建为这个应用程序-一个单一的工作站控制所有三个CCD摄像机,照明,刺激,和步进电机旋转的心脏。几何重建算法改编自以前的心脏成像系统。我们证明了系统的成像多态性心动过速。
A panoramic cardiac imaging system consisting of three highspeed CCD cameras has been developed to image the surface electrophysiology of a rabbit heart via fluorescence imaging using a voltage-sensitive fluorescent dye. A robust, unique mechanical system was designed to accommodate the three cameras and to adapt to the requirements of future experiments. A unified computer interface was created for this application-a single workstation controls all three CCD cameras, illumination, stimulation, and a stepping motor that rotates the heart. The geometric reconstruction algorithms were adapted from a previous cardiac imaging system. We demonstrate the system by imaging a polymorphic cardiac tachycardia.