Linear IgA Dermatosis and Hodgkin's Lymphoma
Linear IgA Dermatosis and Hodgkin's Lymphoma
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线性 IgA 皮肤病和霍奇金淋巴瘤
DOI：
10.1111/j.1346-8138.1990.tb01707.x
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
A. E. Hoven
中科院分区：
文献类型：
--
作者：
W. Jacyk;G. Nagel;A. E. Hoven
一名47岁的南非黑人男性同时诊断为线状伊加皮肤病和霍奇金淋巴瘤。线状伊加皮肤病的皮肤变化对氨苯砜和MOPP方案的联合治疗有反应。先前单独给予氨苯砜没有导致皮肤状况的改善。文献中报告了四例胃肠道外线性伊加皮肤病和淋巴瘤，其中三例为霍奇金型。文献回顾表明，不同形式的淋巴瘤似乎与线性伊加皮肤病和疱疹样皮炎有关。目前的病人代表了第一个免疫学证实的线性伊加皮肤病的情况下，在成年黑人非洲。
Linear IgA dermatosis and Hodgkin's lymphoma were diagnosed at the same time in a 47‐year‐old Black South African man. Skin changes of linear IgA dermatosis responded to a combined treatment with dapsone and MOPP regimen. Prior administration of dapsone alone did not result in improvement of the skin condition. Four documented cases of linear IgA dermatosis and lymphoma outside the gastrointestinal tract, three of them of Hodgkin's type, have been reported in the literature. Review of the literature suggests that different forms of lymphoma seem to be associated with linear IgA dermatosis and dermatitis herpetiformis. The present patient represents the first immunologically verified case of linear IgA dermatosis in an adult Black African.