CHILDREN ABSORB TRIS-BP FLAME-RETARDANT FROM SLEEPWEAR - URINE CONTAINS MUTAGENIC METABOLITE, 2,3-DIBROMOPROPANOL

CHILDREN ABSORB TRIS-BP FLAME-RETARDANT FROM SLEEPWEAR - URINE CONTAINS MUTAGENIC METABOLITE, 2,3-DIBROMOPROPANOL
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DOI:
10.1126/science.684422
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发表时间:
1978-01-01
期刊:
影响因子:
56.9
通讯作者:
THENOT, JP
THENOT, JP
中科院分区:
综合性期刊1区
文献类型:
--
作者:
BLUM, A;GOLD, MD;THENOT, JP

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阻燃剂磷酸三(2,3-二溴丙基)酯 (tris-BP) 是一种诱变剂,会导致动物癌症和不育,被人类从织物中吸收。在 10 名穿着或曾经穿着经过 tris-BP 处理的睡衣的儿童的尿液样本中发现了 2,3-二溴丙醇,这是 tris-BP 的代谢产物,本身也是一种诱变剂。其中八名儿童穿着清洗良好的睡衣,讨论了清洗良好的睡衣吸收 tris-BP 的可能性。在 1 名儿童和 1 名成人(从未穿过 tris-BP 处理的服装)的尿液中未发现 2,3-二溴丙醇。
The flame retardant, tris(2,3-dibromopropyl)phosphate (tris-BP), which is a mutagen and causes cancer and sterility in animals is absorbed from fabric by people. 2,3-Dibromopropanol, a metabolite of tris-BP and a mutagen itself, was found in the urine samples of 10 children who were wearing or who wore-tris-BP-treated sleepwear. Eight of these children were wearing well-washed sleepwear and the possibility of absorption of tris-BP from well-washed sleepwear is discussed. 2,3-Dibromopropanol was not found in the urines of 1 child and 1 adult who never wore tris-BP-treated garments.