Complications and Expected Outcome of Glioma Surgery

Complications and Expected Outcome of Glioma Surgery
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胶质瘤手术的并发症和预期结果

DOI:
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发表时间:
1999
影响因子:
3.9
通讯作者:
J. Piepmeier
J. Piepmeier
中科院分区:
医学2区
文献类型:
--
作者:
K. Vives;J. Piepmeier

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脑内胶质瘤患者的治疗重点是选择延长生存期的治疗方法,同时将并发症的风险降至最低,并保持足够的生活质量。根据作者的经验,低级别胶质瘤患者最好采用大体全切除治疗,以降低较高级别胶质瘤复发的风险。在高级别胶质瘤患者中,年龄、卡诺夫斯基表现状态、组织学和放疗的使用是主要的生存预测因素。手术切除的程度没有这些因素那么重要,但最近的一系列研究表明,接受更广泛手术的患者具有生存优势。手术切除的主要并发症是神经功能损害。在功能磁共振成像和术中标测的辅助下,仔细的术前计划有助于实现最大限度的安全切除。
The management of patients with intracerebral glioma is focused upon the selection of treatment modalities that prolong survival while minimizing the risk of complications and maintaining an adequate quality of life. In the author's experience, patients with low-grade gliomas are best treated with gross total resection in order to decrease the risk of recurrence with higher grade lesions. In patients with high-grade glioma, age, Karnofsky Performance Status, histology and the use of radiotherapy are major predictors of survival. The extent of surgical resection is less important than these factors, but recent series support a survival advantage in patients that undergo more extensive surgery. The major complication from surgical resection is neurologic impairment. Careful preoperative planning with the assistance of functional MRI and intraoperative mapping is useful for accomplishing the maximum safe resection.
动脉瘤性蛛网膜下腔出血的转诊偏倚。
DOI: 10.3171/jns.1993.78.5.0726
发表时间: 1993
影响因子: 4.1
作者:
Whisnant,JP;Sacco,SE;O'Fallon,WM;Fode,NC;SundtJr,TM
通讯作者: SundtJr,TM