Room temperature phosphorescence determination of propranolol in pharmaceutical formulations.
Room temperature phosphorescence determination of propranolol in pharmaceutical formulations.
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室温磷光法测定药物制剂中的普萘洛尔。
DOI：
10.1002/jps.2600720521
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发表时间：
1983
影响因子：
3.8
通讯作者：
Winefordner,JD
中科院分区：
文献类型：
--
作者：
Bateh,RP;Winefordner,JD
采用一种简单、快速、特异的方法分析了制剂中普萘洛尔的含量。将适量的制剂和标准品溶解（稀释）在2m的碘化钾-乙醇-水溶液中，每种溶液取5 μl滴在滤纸上，在室温下测定磷光强度，并将样品信号电平与标准品的信号电平进行比较。结果表明，室温磷光可以很容易地应用于药物配方的分析，其中活性成分通常包含在各种各样的基质中。
A simple, rapid, and specific procedure was used for the analysis of propranolol in pharmaceutical formulations. The procedure consisted of dissolving (diluting) appropriate quantities of preparations and standards in (with) a 2 M potassium iodide–ethanol–water solution, spotting 5 μl of each resultant solution onto filter paper disks, determining the phosphorescence intensities at room temperature, and comparing sample signal levels with those of standards. The results indicated that room temperature phosphorescence can be easily applied to the analysis of pharmaceutical formulations where active ingredients are generally contained in a wide variety of matrices.