Septic pulmonary embolism in Korea: Microbiology, clinicoradio logic features, and treatment outcome
Septic pulmonary embolism in Korea: Microbiology, clinicoradio logic features, and treatment outcome
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DOI：
10.1016/j.jinf.2006.04.008
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发表时间：
2007-03-01
影响因子：
28.2
通讯作者：
Kim, Gun-Woo
中科院分区：
文献类型：
--
作者：
Lee, Seung-Joon;Cha, Seung-Ick;Kim, Gun-Woo
目的：本研究的目的是调查韩国脓毒性肺栓塞（SPE）患者的临床放射学特征、微生物学资料、原发感染部位和治疗结果。方法：我们回顾性分析了21例SPE患者，包括“明确”和“可能”病例。CT表现以周围型结节最多见（89.0%），其次为非结节性浸润（7.0%）和周围型楔形病变（3.2%）。空洞和供血血管征，更具体的SPE被确定在所有病变的10.4%和6%，分别。经胸超声心动图显示13例患者中有3例出现明显异常，经食管超声心动图研究时，5例患者中仅1例发现赘生物。在15例患者中，发现了原发感染部位，并在16：K中分离出3种致病微生物。肺炎链球菌（8）;金黄色葡萄球菌（6）;草绿色链球菌（2）。所有患者均接受肠外抗菌治疗或不引流的肺外感染和18 recovered.Conclusions：虽然SPE的病原体可能会有所不同，这取决于原发灶的感染，早期诊断和及时的抗菌治疗与放射或手术干预，可以导致成功的治疗结果。(C)2006年，英国传染病协会。出版社：Elsevier Ltd. rights reserved.
Objectives: The aim of this study was to investigate the clinicoradiologic features, microbiologic data, primary sites of infection, and treatment results for patients with septic pulmonary embolism (SPE) in Korea.Methods: We retrospectively analyzed 21 SPE patients including "definite" and "probable" cases.Results: On CT scan, peripheral nodules were the most common lesions (89.0%), followed by non-nodular infiltrates (7.0%) and wedge-shaped peripheral lesions (3.2%). Cavitation and feeding vessel sign, more specific to SPE were identified in 10.4% and 6% of all the lesions, respectively. Transthoracic echocardiography revealed significant abnormalities in three of 13 patients with an additional finding of vegetation in only one of five patients when studied by transesophageal echocardiography. In 15 patients, primary sites of infection were found, and three causative organisms were isolated in 16: K. pneumoniae (8); S. aureus (6); and viridans streptococci (2). All patients received parenteral antimicrobial therapy with or without drainage of the extrapulmonary infection and 18 recovered.Conclusions: Although the pathogens of SPE may differ depending on the primary foci of infection, early diagnosis and prompt antimicrobial therapy with radiologic or surgical intervention can lead to a successful treatment outcome. (C) 2006 The British Infection Society. Published by Elsevier Ltd. All. rights reserved.