Hyperjovinols A and B:: Two new phloroglucinol derivatives from Hypericum jovis with antioxidant activity in cell cultures
Hyperjovinols A and B:: Two new phloroglucinol derivatives from Hypericum jovis with antioxidant activity in cell cultures
复制标题
DOI：
10.1021/np034051w
复制
发表时间：
2004-06-01
影响因子：
5.1
通讯作者：
Kletsas, D
中科院分区：
文献类型：
--
作者：
Athanasas, K;Magiatis, P;Kletsas, D
从希腊特有植物金丝桃（Hypericum jovis）的二氯甲烷提取物中分离出两个新的和四个已知的间苯三酚衍生物。在体外用DPPH法和细胞培养中用DCFH-DA法评估其抗氧化活性。所有六种化合物都显示出显著的抗氧化活性，其中两种化合物在细胞水平上具有与Trolox相当的抗ROS活性。
Two new and four known phloroglucinol derivatives were isolated from the dichloromethane extract of the Greek endemic plant Hypericum jovis. Their antioxidant activity was evaluated in vitro with the DPPH assay and in cell cultures using the DCFH-DA assay. All six compounds demonstrated significant antioxidant activity, while two of them possessed activity at a cellular level comparable to Trolox, protecting against ROS.