MOCAT2: a metagenomic assembly, annotation and profiling framework.
MOCAT2: a metagenomic assembly, annotation and profiling framework.
复制标题
DOI：
10.1093/bioinformatics/btw183
复制
发表时间：
2016-08-15
期刊：
影响因子：
--
通讯作者：
Bork P
中科院分区：
文献类型：
--
作者：
Kultima JR;Coelho LP;Forslund K;Huerta-Cepas J;Li SS;Driessen M;Voigt AY;Zeller G;Sunagawa S;Bork P
摘要：MOCAT2是一个用于宏基因组序列组装和基因预测的软件管道，具有分类和功能丰度分析的新功能。通过从涵盖各种功能类别的18个数据库中传播预先计算的分配，自动生成和有效注释非冗余参考目录，可以快速和全面地表征宏基因组的功能。可用性和实现：MOCAT2在Perl 5和Python 2.7中实现，专为64位UNIX系统设计，并通过LSF， PBS或SGE排队系统提供高性能计算机使用支持；源代码在GPL3许可下可在http://mocat.embl.de免费获得。补充信息：补充数据可在Bioinformatics在线获取。
Summary: MOCAT2 is a software pipeline for metagenomic sequence assembly and gene prediction with novel features for taxonomic and functional abundance profiling. The automated generation and efficient annotation of non-redundant reference catalogs by propagating pre-computed assignments from 18 databases covering various functional categories allows for fast and comprehensive functional characterization of metagenomes. Availability and Implementation: MOCAT2 is implemented in Perl 5 and Python 2.7, designed for 64-bit UNIX systems and offers support for high-performance computer usage via LSF, PBS or SGE queuing systems; source code is freely available under the GPL3 license at http://mocat.embl.de. Contact: bork@embl.de Supplementary information: Supplementary data are available at Bioinformatics online.