The HHpred interactive server for protein homology detection and structure prediction.
The HHpred interactive server for protein homology detection and structure prediction.
复制标题
用于蛋白质同源性检测和结构预测的 HHpred 交互式服务器。
DOI:
10.1093/nar/gki408
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发表时间:
2005-07-01
影响因子:
14.9
通讯作者:
Lupas, AN
中科院分区:
文献类型:
--
作者:
Söding, J;Biegert, A;Lupas, AN
HHpred is a fast server for remote protein homology detection and structure prediction and is the first to implement pairwise comparison of profile hidden Markov models (HMMs). It allows to search a wide choice of databases, such as the PDB, SCOP, Pfam, SMART, COGs and CDD. It accepts a single query sequence or a multiple alignment as input. Within only a few minutes it returns the search results in a user-friendly format similar to that of PSI-BLAST. Search options include local or global alignment and scoring secondary structure similarity. HHpred can produce pairwise query-template alignments, multiple alignments of the query with a set of templates selected from the search results, as well as 3D structural models that are calculated by the MODELLER software from these alignments. A detailed help facility is available. As a demonstration, we analyze the sequence of SpoVT, a transcriptional regulator from Bacillus subtilis. HHpred can be accessed at .
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影响因子:
2.9
作者:
Kihara, D;Jeffrey, S
通讯作者:
Jeffrey, S
影响因子:
14.9
作者:
Panchenko, AR
通讯作者:
Panchenko, AR
DOI:
10.1073/pnas.0405913101
发表时间:
2004-10-05
影响因子:
11.1
作者:
Rand, TA;Ginalski, K;Wang, XD
通讯作者:
Wang, XD
影响因子:
14.9
作者:
Pawlak SD;Radlinska M;Chmiel AA;Bujnicki JM;Skowronek KJ
通讯作者:
Skowronek KJ
影响因子:
5.8
作者:
Söding, J
通讯作者:
Söding, J