Endorsement of DSM-IV dependence criteria among caffeine users

Endorsement of DSM-IV dependence criteria among caffeine users
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DOI:
10.1016/s0376-8716(98)00083-0
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发表时间:
1998-10-01
影响因子:
4.2
通讯作者:
Howard, T
Howard, T
中科院分区:
医学2区
文献类型:
--
作者:
Hughes, JR;Oliveto, AH;Howard, T

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这篇文章的目的是确定一些咖啡因使用者是否认可依赖和滥用的临床指标。我们随机选择了162名咖啡因使用者,通过结构化的电话采访,询问了他们在过去一年中使用咖啡因的依赖,滥用,中毒和戒断的DSM-IV标准。对于强烈的愿望或不成功的停止用途:50%用于花费大量时间使用药物,28%用于超过预期使用,18%用于停药,14%用于尽管知道危害仍使用,8%用于耐受性,1%用于前述活动以使用。7%的使用者符合DSM-IV咖啡因中毒的标准,在那些试图永久停止咖啡因的人中,24%符合DSM-IV咖啡因戒断的研究标准。29/30例(97%)同意进行依赖性的重测面谈。八位药物滥用专家临床医生同意自我认可的咖啡因依赖91%的时间。我们的研究结果重复了早期的工作,并表明相当一部分咖啡因使用者表现出依赖性行为。需要进一步研究以确定这类使用者是否表现出临床上显著的药物依赖综合征。(C)1998爱思唯尔科学爱尔兰有限公司保留所有权利。
The purpose of this article is to determine whether some caffeine users endorse clinical indicators of dependence and abuse. We asked 162 randomly-selected caffeine users generic DSM-IV criteria for dependence, abuse, intoxication and withdrawal pertaining to their caffeine use in the last year via a structured telephone interview. The prevalence of endorsement of dependence items was 56% for strong desire or unsuccessful attempt to stop use: 50% for spending a great deal of time with the drug, 28% for using more than intended, 18% for withdrawal, 14% for using despite knowledge of harm, 8% for tolerance and 1% for foregoing activities to use. Seven percent of users met DSM-IV criteria for caffeine intoxication and, among those who had tried to stop caffeine permanently, 24% met DSM-IV research criteria for caffeine withdrawal. Test-retest interviews for dependency agreed in 29/30 cases (97%). Eight expert substance abuse clinicians agreed with self-endorsed caffeine dependence 91% of the time. Our results replicate earlier work and suggest that a substantial proportion of caffeine users exhibit dependence-like behaviors. Further studies are needed to determine whether such users exhibit a clinically significant syndrome of drug dependence. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.