FUNCTIONAL SELECTION FOR THE CENTROMERE DNA FROM YEAST CHROMOSOME-VIII

FUNCTIONAL SELECTION FOR THE CENTROMERE DNA FROM YEAST CHROMOSOME-VIII
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DOI:
10.1093/nar/23.6.922
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发表时间:
1995-03-25
影响因子:
14.9
通讯作者:
HEGEMANN, JH
HEGEMANN, JH
中科院分区:
生物学2区
文献类型:
--
作者:
FLEIG, U;BEINHAUER, JD;HEGEMANN, JH

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着丝粒是真核染色体的重要组成部分。在芽殖酵母中,迄今为止,16个着丝粒DNA中的15个已被分离。在这里,我们报告CEN8的功能分离和表征,最后一个酵母着丝粒丢失。着丝粒的一致序列的16条染色体在这种生物体。
Centromeres are essential components of eucaryotic chromosomes. In budding yeast, up to now, 15 of the 16 centromere DNAs have been isolated. Here we report the functional isolation and characterization of CEN8, the last of the yeast centromeres missing. The centromere consensus sequence for the 16 chromosomes in this organism is presented.