The concept of multifactorial etiology of cancer.

The concept of multifactorial etiology of cancer.
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癌症多因素病因学的概念。

DOI:
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发表时间:
1993
期刊:
Acta Pharmacologica et Toxicologica
影响因子:
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通讯作者:
K. Overvad
K. Overvad
中科院分区:
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文献类型:
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作者:
J. Olsen;K. Overvad

文献摘要

被引文献

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原因的概念不仅仅是专业哲学家讨论的。流行病学家还必须澄清如何使用这一概念,因为它的含义对理解疾病-疾病关联的基本措施具有深远的影响。在设计研究或分析流行病学数据时,原因的概念也很重要。本文阐述了组分致因模型及其与疾病作用机制的关系。还提出了一种基于组件原因模型的交互措施。根据健康信念模式,原因的常识概念对于健康预防方案的成功也起着根本作用。在只有少数受影响者感染方案往往要预防的疾病的情况下,组成原因模式可以澄清因果模式。
The concept of causes is not just for professional philosophers to discuss. The epidemiologists also have to clarify how the concept is used since its meaning has profound implications for understanding basic measures of exposure-disease association. The concept of cause also has importance when designing a study or when analyzing epidemiological data. The paper describes the components cause model and its relationship with the mechanism of disease action. A measure of interaction is also presented which is based upon the components cause model. The common sense concept of causes also plays a fundamental role for the success of a health preventive programme according to the Health Belief Model. The component cause model may clarify causal patterns in situations when only a few of the exposed get the disease which the programme tends to prevent.