Finite element modeling of the viscoelastic responses of the eye during microvolumetric changes.
Finite element modeling of the viscoelastic responses of the eye during microvolumetric changes.
复制标题
微体积变化期间眼睛粘弹性响应的有限元建模。
DOI：
10.4236/jbise.2013.612a005
复制
发表时间：
2013-12
期刊：
影响因子：
--
通讯作者：
Liu J
中科院分区：
文献类型：
--
作者：
Perez BC;Morris HJ;Hart RT;Liu J
建立了一个线性粘弹性有限元模型，以研究在三种不同速率下，由于眼睛中的微体积变化而引起的眼内压（IOP）升高的影响因素。角膜和巩膜的粘弹性，包括瞬时模量，平衡模量，和松弛时间常数，参数变化，以检查其对IOP升高的影响，在不同的体积变化率。模拟的反应与先前报道的从猪眼球获得的实验结果非常一致，显示出以更快的速率升高IOP的总体趋势。模拟结果表明，由于体积变化，所有粘弹性都会影响动态IOP的分布，并且特定参数的相对重要性高度依赖于变化率。
A linear viscoelastic finite element model was built to investigate factors that influenced the intraocular pressure (IOP) elevations due to micro-volumetric changes in the eye at three different rates. The viscoelastic properties of the cornea and the sclera, including the instantaneous modulus, equilibrium modulus, and relaxation time constants, parametrically varied to examine their effects on IOP elevations at different rates of volumetric changes. The simulated responses were in good agreement with the previously reported experimental results obtained from porcine globes, showing the general trend of higher IOP elevations at faster rates. The simulations showed that all viscoelastic properties influenced the profile of the dynamic IOP due to volumetric changes, and the relative significance of a specific parameter was highly dependent on the rate of change.