Highly enantioselective synthesis of cyclic and functionalized α-amino acids by means of a chiral phase transfer catalyst
Highly enantioselective synthesis of cyclic and functionalized α-amino acids by means of a chiral phase transfer catalyst
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DOI：
10.1016/s0040-4039(98)01067-3
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发表时间：
1998-07-23
影响因子：
1.8
通讯作者：
Xu, F
中科院分区：
文献类型：
--
作者：
Corey, EJ;Noe, MC;Xu, F
手性季铵盐1作为相转移催化剂，使甘氨酸衍生物2在烷基化反应和Michael加成反应中对映选择性转化为多种环和无环手性α -氨基酸，对映选择性高达200:1。1998爱思唯尔科学有限公司版权所有。
The chiral quaternary ammonium salt 1 serves as phase transfer catalyst for the enantioselective conversion of the glycine derivative 2 to a variety of cyclic and acyclic chiral alpha-amino acids with enantioselectivities as high as 200:1 in alkylation and Michael addition reactions. (C) 1998 Elsevier Science Ltd. All rights reserved.