Associations with intraocular pressure in latinos: The Los Angeles Latino Eye Study
Associations with intraocular pressure in latinos: The Los Angeles Latino Eye Study
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DOI：
10.1016/j.ajo.2008.03.015
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发表时间：
2008-07-01
影响因子：
4.2
通讯作者：
Varma, Rohit
中科院分区：
文献类型：
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作者：
Memarzadeh, Farnaz;Ying-Lai, Me;Varma, Rohit
目得：为了评估与眼内压（lop）在拉丁美洲population.DESIGN：人口为基础的横断面study.METHODS：拉丁美洲人40岁及以上（n = 5，958）从洛杉矶拉丁美洲眼科研究没有一个历史的眼部水肿治疗接受了采访者管理的问卷调查和一个完整的眼部和临床检查。通过压平眼压测量法获得LOP，并基于三次测量的平均值。采用多元回归模型分析生物学因素与LOP.Results的独立相关性：收缩压升高、角膜中央厚度增加和糖尿病是LOP.Results升高的主要相关因素。其他正相关变量包括年龄、女性、舒张压升高、体重指数增大、虹膜颜色加深和核硬化。眼轴长度和青光眼家族史与LOP.CONCLUSIONS：几个系统和眼部特征与拉丁美洲人的LOP升高相关。通过识别和认识这些风险因素，我们可以定义可能最有可能患上高脂血症的人群亚组。
PURPOSE: To evaluate the association of biologic factors with intraocular pressure (lop) in a Latino population.DESIGN: Population,based cross-sectional study.METHODS: Latinos 40 years and older (n = 5,958) from the Los Angeles Latino Eye Study without a history of ocular hypotensive treatment underwent an interviewer-administered questionnaire and a complete ocular and clinical examination. lop was obtained by applanation tonometry and was based on the mean of three measurements. Multivariable regression models were used to evaluate the independent association of biological factors with lop.RESULTS: Higher systolic blood pressure, higher central corneal thickness, and diabetes mellitus were the major factors associated with elevated lop. Other positively correlated variables included age, female gender, higher diastolic blood pressure, larger body mass index, darker colored irides, and nuclear sclerosis. Axial length and family history of glaucoma had no association with lop.CONCLUSIONS: Several systemic and ocular characteristics are associated with elevated lop in Latinos. By identifying and recognizing these risk factors, we can define subgroups of the population that may be most at risk of having elevated lop.