Nanosensors for the detection of hydrogen peroxide
Nanosensors for the detection of hydrogen peroxide
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DOI：
10.1016/j.elecom.2013.12.015
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发表时间：
2014-03-01
影响因子：
5.4
通讯作者：
Schuhmann, Wolfgang
中科院分区：
文献类型：
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作者：
Clausmeyer, Jan;Actis, Paolo;Schuhmann, Wolfgang
普鲁士蓝(PB)沉积在纳米电极上，是制作电流型过氧化氢传感器的基础。在石英纳米柱中丁烷的热解制备了碳纳米电极，并在形成的纳米腔中沉积了PB。这种方法显著提高了PB膜的稳定性，同时在中性pH值下保持了50A moL(-1)L cm(-2)的高平均检测灵敏度(-50 mV对Ag/AgCl0.1MCl-)。过氧化氢在10~3 mM的浓度范围内选择性定量。我们设想将这些纳米传感器应用于活细胞中氧化应激的细胞内监测。(C)2013爱思唯尔B.V.保留所有权利。
Prussian Blue (PB) deposited on a nanoelectrode is the basis for an amperometric hydrogen peroxide sensor. Carbon nanoelectrodes, fabricated from pyrolytic decomposition of butane within a quartz nanopipette, were electrochemically etched and PB was deposited in the formed nanocavity. This procedure significantly increased the stability of PB films while maintaining a high mean sensitivity of 50 A mol(-1) l cm(-2) for H2O2 detection at -50 mV vs. Ag/AgCl (0.1 M Cl-) at neutral pH value. Hydrogen peroxide was selectively quantified in the concentration range from 10 mu M to 3 mM. We envision the application of these nanosensors to the intracellular monitoring of oxidative stress in living cells. (C) 2013 Elsevier B.V. All rights reserved.