Methodological issues in longitudinal epidemiologic studies of dental caries.

Methodological issues in longitudinal epidemiologic studies of dental caries.
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龋齿纵向流行病学研究的方法学问题。

DOI:
10.1111/j.1600-0528.1998.tb02017.x
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发表时间:
1998
影响因子:
2.3
通讯作者:
D. Caplan
D. Caplan
中科院分区:
医学3区
文献类型:
--
作者:
G. Slade;D. Caplan

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随着龋齿的纵向流行病学研究解决越来越复杂的研究问题,分析这些研究的数据的方法变得更加复杂。这篇综述考察了可用于分析和报告此类研究的数据的方法。在龋病纵向研究中,传统的分析方法使用DMFS增量作为结果度量。然而,可能需要另外两个结果指标来解决一些研究问题:累积发病率,量化龋齿风险;以及发病率密度,量化龋齿比率。在计算DMF增量时,必须处理四个主要的分析决策:检查人员的错误分类(“反向”)、因龋齿而丢失的牙齿、两次以上检查的结果以及多种事件,如龋齿的发生和发展。我们提出了一种用于枚举龋病事件的统一方法,该方法允许将在计算DMFS增量时做出的相同的分析决定应用于累积发病率和发病率密度的计算。考虑到在龋齿纵向研究中列举事件时必须做出的各种分析决定,作者应该具体说明如何处理所有可能的龋齿状态变化。此外,如果一项研究使用一种以上的结果衡量标准,则在计算这些衡量标准时,应使用相同的决定来列举事件。
As longitudinal epidemiologic studies of dental caries address increasingly complex research questions, approaches to analysis of data from those studies have become more sophisticated. This review examines methods available for analyzing and reporting data from such studies. Traditional analytic methods utilize the DMFS increment as the outcome measure in longitudinal studies of caries. However, two other outcome measures may be needed to address some research issues: cumulative incidence, which quantifies caries risk; and incidence density, which quantifies caries rate. Four major analytic decisions have to be addressed when computing DMFS increment: examiner misclassification ("reversals"), teeth lost due to caries, findings from more than two examinations, and multiple events such as caries initiation and progression. We present a uniform approach for enumerating caries events that permits the same analytic decisions made in calculating DMFS increment to be applied to cumulative incidence and incidence density calculations. In view of the variety of analytic decisions that must be made when enumerating events in longitudinal studies of caries, authors should specify how all potential changes in caries status were handled. Furthermore, if a study uses more than one outcome measure, the same decisions for enumerating events should be used when computing those measures.
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DOI: 10.1111/j.1600-0528.1997.tb00898.x
发表时间: 1997
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