Peripapillary Retinoschisis in Glaucoma Patients.
Peripapillary Retinoschisis in Glaucoma Patients.
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DOI：
10.1155/2016/1612720
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发表时间：
2016
影响因子：
1.9
通讯作者：
Izgi B
中科院分区：
文献类型：
--
作者：
Bayraktar S;Cebeci Z;Kabaalioglu M;Ciloglu S;Kir N;Izgi B
目的.目的：应用光谱域光学相干断层扫描（SD-OCT）技术，研究青光眼患者视乳头周围视网膜劈裂及其对视网膜神经纤维层（RNFL）厚度的影响。方法.回顾性分析了940例青光眼患者（第1组）和801例疑似青光眼患者（第2组）的SD-OCT视乳头周围RNFL（cpRNFL）B超图像。探讨视网膜劈裂的结构和临床特点。在视网膜劈裂诊断时和随访时进行的RNFL厚度测量也进行了比较。结果第1组940例青光眼患者中有26例（3.1%）发现了29个视网膜劈裂区域，第2组801例患者（0.87%）发现了7个区域。视网膜劈裂与视网膜神经纤维层缺损重叠，与视神经盘粘连。在视网膜劈裂时，颞下象限的RNFL厚度与随访扫描相比在统计学上更大（p < 0.001）。未观察到黄斑受累或视网膜脱离。结论本研究调查了33例视乳头周围视网膜劈裂患者。在视网膜劈裂时观察到RNFL厚度测量值增加。检查青光眼患者的cpRNFL B扫描图像，以便RNFL厚度不被高估是很重要的。
Purpose. To investigate peripapillary retinoschisis and its effect on retinal nerve fiber layer (RNFL) thickness measurements by using spectral-domain optical coherence tomography (SD-OCT) in glaucomatous eyes. Methods. Circumpapillary RNFL (cpRNFL) B-scan images of 940 glaucoma patients (Group 1) and 801 glaucoma-suspect patients (Group 2) obtained by SD-OCT were reviewed. The structural and clinical characteristics of the retinoschisis were investigated. The RNFL thickness measurements taken at the time of retinoschisis diagnosis and at the follow-up visits were also compared. Results. Twenty-nine retinoschisis areas were found in 26 of the 940 glaucoma patients (3.1%) in Group 1 and seven areas were found in 801 patients (0.87%) in Group 2. In glaucomatous eyes, the retinoschisis was attached to the optic disc and overlapped with the RNFL defect. At the time of retinoschisis, the RNFL thickness was statistically greater in the inferior temporal quadrant when compared with the follow-up scans (p < 0.001). No macular involvement or retinal detachment was observed. Conclusion. The present study investigated 33 peripapillary retinoschisis patients. Increase in RNFL thickness measurements was observed at the time of retinoschisis. It is important to examine the cpRNFL B-scan images of glaucoma patients so that the RNFL thickness is not overestimated.