Using high-density perimetry to explore new approaches for characterizing visual field defects.
Using high-density perimetry to explore new approaches for characterizing visual field defects.
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DOI：
10.1016/j.visres.2023.108259
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发表时间：
2023-09
期刊：
影响因子：
1.8
通讯作者：
Swanson, W. H.
中科院分区：
文献类型：
--
作者：
Marin-Franch, I.;Wyatt, H. J.;Swanson, W. H.
高密度阈值视野检查发现，传统的静态阈值视野检查由于采样不足而错过缺陷。然而，高密度测试可能既慢又受正常注视眼球运动的限制。我们通过研究健康眼血管瘤的高密度视野检查结果的显示来探索替代方法，血管阴影中敏感性降低的区域。四名健康成年人的右眼用数字光检眼镜进行测试，该检眼镜在呈现视觉刺激的同时收集视网膜图像。这些图像用于推断每次试验的刺激位置。在13°×19°矩形网格的247个位置测量Goldmann III尺寸刺激的对比度阈值，间隔0.5°，水平延伸11°至17°，垂直延伸-3 °至+6°，覆盖视神经乳头的一部分和几个主要血管。周边灵敏度的地图确定了血管附近灵敏度降低的弥漫性区域，但这些显示出中等的结构-功能一致性，当考虑到眼睛位置的影响时，仅略有改善。一个创新的方法称为切片显示被用来定位区域的敏感性降低。切片显示表明，更少的试验可以产生类似的结构-功能一致性。这些结果表明，通过关注缺陷位置而不是敏感度图，可以显著缩短测试持续时间。传统阈值视野检查的这种替代方案具有在不需要高密度阈值视野检查的大量时间需求的情况下映射缺陷的形状的潜力。模拟说明了这样的算法可以操作。
High-density threshold perimetry has found that conventional static threshold perimetry misses defects due to undersampling. However, high-density testing can be both slow and limited by normal fixational eye movements. We explored alternatives by studying displays of high-density perimetry results for angioscotomas in healthy eyes—areas of reduced sensitivity in the shadows of blood vessels. The right eyes of four healthy adults were tested with a Digital Light Ophthalmoscope that gathered retinal images while presenting visual stimuli. The images were used to infer stimulus location on each trial. Contrast thresholds for a Goldmann size III stimulus were measured at 247 locations of a 13°×19° rectangular grid, with separation 0.5°, extending from 11° to 17° horizontally and − 3° to +6° vertically, covering a portion of the optic nerve head and several major blood vessels. Maps of perimetric sensitivity identified diffuse regions of reduced sensitivity near the blood vessels, but these showed moderate structure–function agreement that was only modestly improved when effects of eye position were accounted for. An innovative method termed slice display was used to locate regions of reduced sensitivity. Slice display demonstrated that many fewer trials could yield similar structure–function agreement. These results are an indication that test duration might be reduced dramatically by focusing on location of defects rather than maps of sensitivity. Such alternatives to conventional threshold perimetry have the potential to map the shape of defects without the extensive time demands of high-density threshold perimetry. Simulations illustrate how such an algorithm could operate.
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影响因子：
1.8
作者：
Swanson, William H.;Dul, Mitchell W.;Horner, Douglas G.;Malinovsky, Victor E.
通讯作者：
Malinovsky, Victor E.
影响因子：
4.4
作者：
Hot, Aliya;Dul, Mitchell W.;Swanson, William H.
通讯作者：
Swanson, William H.
影响因子：
17.8
作者：
Hood DC;Raza AS;de Moraes CG;Liebmann JM;Ritch R
通讯作者：
Ritch R
DOI：
10.1007/bf02173350
发表时间：
1986-01-01
影响因子：
2.7
作者：
FLAMMER, J
通讯作者：
FLAMMER, J
影响因子：
1.8
作者：
KOCH, P;ROULIER, A;FANKHAUSER, F
通讯作者：
FANKHAUSER, F