Emerging Gram-Negative Infections in Burn Wounds
Emerging Gram-Negative Infections in Burn Wounds
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DOI：
10.1097/bcr.0b013e31822ac7e6
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发表时间：
2011-09-01
影响因子：
1.4
通讯作者：
Dickson, William A.
中科院分区：
文献类型：
--
作者：
Azzopardi, Ernest A.;Azzopardi, Sarah M.;Dickson, William A.
革兰氏阴性菌感染仍然是发病率、死亡率和护理费用的主要因素。在缺乏针对烧伤患者的比较性多国流行病学研究的情况下，我们试图回顾过去60年来新兴革兰氏阴性烧伤伤口感染的文献趋势。绘制这些生物体的趋势图，尽管与北美传染病学会目前针对的六种“ESKAPE”病原体相比是少数，但将在不久的将来确定烧伤医生日益关注的病原体，并开发可能预测感染易感性的患者档案。嗜水气单胞菌感染被确定为值得注意的新兴病原体，占已确定出版物的76%。A.气单胞菌属中，铜绿假单胞菌占96%。死亡率10.7%。以下患者特征表明易感染气单胞菌：平均年龄（平均33.7岁，范围17
Gram-negative infection remains a major contributor to morbidity, mortality, and cost of care. In the absence of comparative multinational epidemiological studies specific to burn patients, we sought to review literature trends in emerging Gram-negative burn wound infections within the past 60 years. Mapping trends in these organisms, although in a minority compared with the six "ESKAPE" pathogens currently being targeted by the Infectious Diseases Society of North America, would identify pathogens of increasing concern to burn physicians in the near future and develop patient profiles that may predict susceptibility to infection. Aeromonas hydrophila infection was identified as the emerging pathogen of note, constituting 76% of the identified publications. A. hydrophila constituted 96% of Aeromonas spp. isolates (mortality 10.7%). The following patient profile indicated predisposition to Aeromonas infection: mean age (mean 33.7 years, range 17