Persistence of virus-reactive serum immunoglobulin M antibody in confirmed West Nile virus encephalitis cases
Persistence of virus-reactive serum immunoglobulin M antibody in confirmed West Nile virus encephalitis cases
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DOI：
10.3201/eid0903.020531
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发表时间：
2003-03-01
影响因子：
11.8
通讯作者：
Campbell, GL
中科院分区：
文献类型：
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作者：
Roehrig, JT;Nash, D;Campbell, GL
对29例实验室确诊的西尼罗河病毒（WNV）脑炎患者连续流血的，以测定WNV反应性免疫球蛋白（IG）M活性。在这些流血的的患者中，7/12（60%）在发病后约500天有抗WNV IgM。临床医生在解释早期季节西尼罗河病毒IgM阳性患者的血清学结果时应谨慎。
Twenty-nine laboratory-confirmed West Nile virus (WNV) encephalitis patients were bled serially so that WNV-reactive immunoglobulin (Ig) M activity could be determined. Of those patients bled, 7 (60%) of 12 had anti-WNV IgM at approximately 500 days after onset. Clinicians should be cautious when interpreting serologic results from early season WNV IgM-positive patients.