Remediation of refractive amblyopia by optical correction alone

Remediation of refractive amblyopia by optical correction alone
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DOI:
10.1046/j.1475-1313.2002.00034.x
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发表时间:
2002-07-01
影响因子:
2.9
通讯作者:
Fielder, A
Fielder, A
中科院分区:
医学2区
文献类型:
--
作者:
Moseley, MJ;Neufeld, M;Fielder, A

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弱视是儿童最常见的视力异常,其特征是通常只有一只眼睛的视力下降。治疗的目的是促进弱视眼的功能,并通过限制,通常通过闭塞,竞争优势的同伴的眼睛。最近的实验证据表明,视力恢复后,早期剥夺是通过增加视觉诱发活动促进。人类的类似方法是在治疗前通过纠正屈光不正来最大限度地减少图像模糊——这种做法可能解释了有时被归因于“眼镜适应”的难以量化的视力改善。在这里,我们描述了在4-24周的时间里,一组仅仅由于屈光不正而引起的弱视儿童的视力获得了临床显著的改善。讨论了屈光性弱视临床治疗的后果。
Amblyopia - the commonest vision abnormality of childhood - is characterized by a loss of visual acuity usually of one eye only. Treatment aims to promote function of the amblyopic eye and does this by restricting, usually through occlusion, the competitive advantage of the fellow eye. Recent experimental evidence demonstrates that the recovery of vision following early deprivation is facilitated by increasing visually evoked activity. An analogous approach in humans is to minimise image blur by correcting refractive error prior to treatment - a practice which may account for the poorly quantified improvements in visual acuity sometimes attributed to 'spectacle adaptation'. Here we describe clinically significant gains in visual acuity obtained over a period of 4-24 weeks in a group of amblyopic children arising solely in response to the correction of refractive error. Consequences for the clinical management of refractive amblyopia are discussed.