Spontaneous dynamics and response properties of a Hodgkin-Huxley-type neuron model driven by harmonic synaptic noise.
Spontaneous dynamics and response properties of a Hodgkin-Huxley-type neuron model driven by harmonic synaptic noise.
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DOI：
10.1140/epjst/e2010-01282-3
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发表时间：
2010-09
期刊：
影响因子：
--
通讯作者：
Neiman AB
中科院分区：
文献类型：
--
作者：
Nguyen H;Neiman AB
We study statistical properties, response dynamics, and information transmission in a Hodgkin-Huxley–type neuron system, modeling peripheral electroreceptors in paddlefish. In addition to sodium and potassium currents, the neuron model includes fast calcium and slow afterhyperpolarization (AHP) potassium currents. The synaptic transmission from sensory epithelium is modeled by a Poission process with a rate modulated by narrow-band noise, mimicking stochastic epithelial oscillations observed experimentally. We study how the interplay of parameters of AHP current and synaptic noise affects the statistics of spontaneous dynamics and response properties of the system. In particular, we confirm predictions made earlier with perfect integrate and fire and phase neuron models that epithelial oscillations enhance stimulus–response coherence and thus information transmission in electroreceptor system. In addition, we consider a strong stimulus regime and show that coherent epithelial oscillations may reduce variability of electroreceptor responses to time-varying stimuli.
