A Convenient One-Pot Procedure for the Synthesis of 2-Aryl Quinazolines Using Active MnO2 as Oxidant

A Convenient One-Pot Procedure for the Synthesis of 2-Aryl Quinazolines Using Active MnO2 as Oxidant
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以活性MnO2为氧化剂一锅法合成2-芳基喹唑啉

DOI:
10.1002/jhet.444
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发表时间:
2010-09-01
影响因子:
2.4
通讯作者:
Pike, Victor W.
Pike, Victor W.
中科院分区:
化学3区
文献类型:
--
作者:
Peng, Yi-Yuan;Zeng, Yuyun;Pike, Victor W.

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以2-氨基苄胺和芳醛为原料,经缩合反应得到2-芳基-1,2,3,4-四氢喹唑啉,再经MnO 2氧化,合成了一系列2-芳基喹唑啉类化合物。
A variety of 2-aryl quinazolines were synthesized from the condensation of 2-aminobenzylamines and aryl aldehydes to form 2-aryl-1,2,3,4-tetrahydroquinazolines and subsequent oxidation of the intermediates with MnO2.