Use of dual-energy computed tomography for the evaluation of calcinosis in patients with systemic sclerosis.
Use of dual-energy computed tomography for the evaluation of calcinosis in patients with systemic sclerosis.
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DOI：
10.1007/s10067-015-2998-7
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发表时间：
2015-09
影响因子：
3.4
通讯作者：
Schlesinger N
中科院分区：
文献类型：
--
作者：
Hsu V;Bramwit M;Schlesinger N
我们研究了双能量计算机断层扫描（DECT）在评估症状性系统性硬化症（SSc）相关的手部钙质沉着症中的有用性。我们对16例有症状的SSCC-钙质沉着症患者的手部进行了DECT扫描，以更好地描述钙质沉着症及其在软组织中的位置，并排除尿酸盐（MSU）晶体沉积。我们还比较了他们的计算机断层扫描（CT）图像，一只手的平片。收集该队列的相关临床信息。16例SSc患者接受了DECT和手部X线平片成像。在我们的队列中，16名SSc患者中有5名患有重叠疾病，即类风湿性关节炎（RA）和/或肌病。钙质沉着症的症状包括疼痛的沉积物（88%）、软组织肿胀（66%）和这些沉积物引起的复发性感染（44%）。在DECT上，钙质沉积物的颜色和密度与骨相同，未发现MSU。然而，他们的CT图像显示软组织中钙质沉积物的位置以及骨破坏的细节更好，特别是如果有覆盖的大块沉积物或屈曲挛缩。这些沉积物最常见于指尖的皮下脂肪垫、沿着肌腱和肌肉群或腕管内。DECT未证实我们的钙质沉着症队列中存在MSU。然而，CT成像是上级平片在定位这些存款的软组织，可能是一个有用的工具，研究SSCC-钙质沉着影响的手，特别是在设置进行性手畸形。
We examined the usefulness of dual-energy computed tomography (DECT) in the evaluation of symptomatic systemic sclerosis (SSc)-related calcinosis of the hands. We performed DECT scan of the hands in 16 patients with symptomatic SSc-calcinosis to better characterize the calcinosis, their locations within the soft tissues, and exclude monosodium urate (MSU) crystal deposition. We also compared their computed tomography (CT) images to plain radiographs of one hand. Pertinent clinical information from this cohort was collected. Sixteen SSc patients underwent DECT and plain X-ray imaging of the hands. Five of the 16 SSc patients in our cohort had overlap disease, either rheumatoid arthritis (RA) and/or myopathy. Calcinosis symptoms included painful deposits (88 %), soft tissue swelling (66 %), and recurrent infections (44 %) from these deposits. On DECT, calcinosis deposits had the same color and density as the bone and no MSU was found. However, their CT images showed better details of the calcinosis locations in the soft tissues as well as the bone destruction, especially if there was overlying bulky deposits or flexion contractures. These deposits were most commonly found in the subcutaneous fat pads of the fingertips, along tendon and muscle groups, or within the carpal tunnel. DECT did not confirm MSU in our cohort with calcinosis. However, CT imaging was superior to plain radiographs in locating these deposits within the soft tissues and may be a useful tool to study SSc-calcinosis affecting the hands, particularly in the setting of progressive hand deformities.