Risk factors for nosocomial bloodstream infections.
Risk factors for nosocomial bloodstream infections.
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院内血流感染的危险因素。
DOI：
10.12968/bjon.2003.12.12.11334
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发表时间：
2003
影响因子：
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通讯作者：
T. Katostaras
中科院分区：
文献类型：
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作者：
Eleni Apostolopolou;G. Katsaris;T. Katostaras
对205例患者进行回顾性研究，以确定与院内血流感染（BSI）相关的危险因素。该研究在希腊雅典的四个内科外科重症监护病房（icu）进行了为期5个月的研究。采用单因素和多因素分析确定危险因素。院内BSI 35例（17.1%）。BSI的发病率密度（定义为BSI的新病例数除以研究人群的总患者日；Jarvis, 1997）为14.3 / 1000患者日（患者在选定时间段内在ICU的总天数）。多变量模型显示，只有3个因素对院内BSI有显著且独立的影响：ICU住院时间（调整优势比（AOR） 1.052, 95%可信区间（CI） 1.018-1.087, P = 0.002）；入院时存在外伤（AOR 2.622, 95% CI 1.074 ~ 6.404, P = 0.034）；院内呼吸机相关性肺炎（AOR 6.153, 95% CI 2.305 ~ 16.422, P = 0.000）。这些结果表明，对院内BSI发展影响最大的因素是与患者在ICU住院期间接受的治疗相关的因素。
A retrospective study of 205 patients was performed to identify the risk factors associated with nosocomial bloodstream infection (BSI). The study occurred during a 5-month period in four medical-surgical intensive care units (ICUs) in Athens, Greece. Risk factors were determined using single and multivariate analyses. Thirty-five patients developed nosocomial BSI (17.1%). The incidence density (defined as the number of new cases of BSI divided by the total of patient-days in the population studied; Jarvis, 1997) of BSI was 14.3 per 1000 patient-days (total number of days that patients are in the ICU during the selected time period). A multivariate model showed that only three factors were significantly and independently responsible for nosocomial BSI: the length of ICU stay (adjusted odds ratios (AOR) 1.052, 95% confidence interval (CI) 1.018-1.087, P = 0.002); the presence of trauma at admission (AOR 2.622, 95% CI 1.074-6.404, P = 0.034); and nosocomial ventilator-associated pneumonia (AOR 6.153, 95% CI 2.305-16.422, P = 0.000). These results show that the factors that had most influence on the development of nosocomial BSI were those factors associated with the treatment received by patients during ICU stay.