Age-related decline in neurogenesis: old cells or old environment?
Age-related decline in neurogenesis: old cells or old environment?
复制标题
与年龄相关的神经发生衰退：旧细胞还是旧环境？
DOI：
10.1002/jnr.10384
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Martin,GeorgeM
中科院分区：
文献类型：
--
作者：
Zitnik,Galynn;Martin,GeorgeM
Neural stem cells are defined as cells that are capable of producing additional undifferentiated stem cells as well as progeny that go on to differentiate into several cellular phenotypes: neurons, glial cells and oligodendrocytes. Neural progenitor cells are defined as cells with a limited replicative potential that are committed to the neuronal lineage. Neural progenitors are derived from neural stem cells either during fetal development or in the adult. Neurogenesis, the production of new neurons, depends upon neural stem cells and neural progenitors being present and responsive to induction. Neurogenesis can be assessed in vitro (Fig. 1) or in vivo.
