Can atmospheric pollution be considered a co-factor in extremely high level of SARS-CoV-2 lethality in Northern Italy?
Can atmospheric pollution be considered a co-factor in extremely high level of SARS-CoV-2 lethality in Northern Italy?
复制标题
DOI：
10.1016/j.envpol.2020.114465
复制
发表时间：
2020-06-01
影响因子：
8.9
通讯作者：
Caro, Dario
中科院分区：
文献类型：
--
作者：
Conticini, Edoardo;Frediani, Bruno;Caro, Dario
本文研究了北方意大利严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）高致死率与大气污染之间的相关性。事实上，伦巴第大区和艾米利亚-罗马涅大区是意大利病毒致死率最高的地区，也是欧洲污染最严重的地区之一。基于这种相关性，本文分析了污染与急性呼吸窘迫综合征的发展和最终死亡之间的可能联系。我们提供的证据表明，生活在污染物水平高的地区的人更容易患上慢性呼吸道疾病，并适合任何感染性病原体。此外，长期暴露于空气污染会导致慢性炎症刺激，即使在年轻和健康的受试者中也是如此。我们的结论是，在北方意大利的高水平的污染应被认为是在该地区记录的高水平的致命性的一个额外的辅助因素。(C)2020爱思唯尔有限公司版权所有。
This paper investigates the correlation between the high level of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) lethality and the atmospheric pollution in Northern Italy. Indeed, Lombardy and Emilia Romagna are Italian regions with both the highest level of virus lethality in the world and one of Europe's most polluted area. Based on this correlation, this paper analyzes the possible link between pollution and the development of acute respiratory distress syndrome and eventually death. We provide evidence that people living in an area with high levels of pollutant are more prone to develop chronic respiratory conditions and suitable to any infective agent. Moreover, a prolonged exposure to air pollution leads to a chronic inflammatory stimulus, even in young and healthy subjects. We conclude that the high level of pollution in Northern Italy should be considered an additional co-factor of the high level of lethality recorded in that area. (C) 2020 Elsevier Ltd. All rights reserved.