Executive function as a mediating factor between visual acuity and postural stability in cognitively healthy adults and adults with Alzheimer's dementia.
Executive function as a mediating factor between visual acuity and postural stability in cognitively healthy adults and adults with Alzheimer's dementia.
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DOI：
10.1016/j.archger.2020.104078
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发表时间：
2020-07-01
影响因子：
4
通讯作者：
Wittich, Walter
中科院分区：
文献类型：
--
作者：
Hunter, Susan W;Divine, Alison;Wittich, Walter
背景：跌倒在老年人中很常见，尤其是患有阿尔茨海默氏痴呆症 (AD) 的老年人。视力和平衡障碍是老年人跌倒的重要危险因素。然而，最近关于认知障碍患者的文献表明，执行功能（EF）对于跌倒风险评估很重要。研究目标是：1) 比较 AD 患者、健康老年人 (OA) 和健康年轻人 (YA) 之间的平衡能力，2) 量化视力和 EF 对姿势稳定性的相互作用。方法：我们招募了 165 名个体（51 名 YA、48 名 OA 和 66 名 AD）。跟踪测试（A 和 B）量化了 EF，Colenbrander 混合对比图测量了高对比度和低对比度视力。加速度计记录了感觉统合改良测试期间的姿势摇摆。双向重复测量方差分析检查了各组之间的姿势摇摆差异。中介分析量化了 EF 在对比敏感度和姿势摇摆之间的关系。 结果：观察到显着的 EF 和视力组间差异 (p
BACKGROUND: Falls in older adults, notably those with Alzheimer's dementia (AD), are prevalent. Vision and balance impairments are prominent falls risk factors in older adults. However, recent literature in the cognitively impaired suggests that executive function (EF) is important for falls risk assessments. The study objectives were to: 1) to compare balance among people with AD, healthy older adults (OA), and healthy young adults (YA) and 2) to quantify the interaction of visual acuity and EF on postural stability.METHODS: We recruited 165 individuals (51 YA, 48 OA, and 66 AD). Trail Making Tests (A and B) quantified EF and the Colenbrander mixed contrast chart measured high and low contrast visual acuity. Accelerometers recorded postural sway during the Modified Test for Sensory Integration. A two-way repeated measures ANOVA examined postural sway differences across groups. Mediation analysis quantified the association of EF in the relationship between contrast sensitivity and postural sway.RESULTS: Significant EF and visual acuity between-group differences were observed (p