Interfacial nano-biosensing in microfluidic droplets for high-sensitivity detection of low-solubility molecules.
Interfacial nano-biosensing in microfluidic droplets for high-sensitivity detection of low-solubility molecules.
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DOI：
10.1039/c5cc09066k
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发表时间：
2016-02-28
期刊：
影响因子：
--
通讯作者：
Li X
中科院分区：
文献类型：
--
作者：
Dou M;García JM Jr;Zhan S;Li X
利用微流控液滴高表面积体积比的特性，我们开发了一种基于适配体功能化氧化石墨烯纳米传感器的界面纳米传感策略，用于高灵敏度一步检测17β-雌二醇和其他低溶解度分子，检测灵敏度比传统系统提高了约3个数量级。
Taking advantage of the property of high surface-area-to-volume ratio of microfluidic droplets, we developed an innovative interfacial nanosensing strategy based on aptamer-functionalized graphene oxide nanosensors in microfluidic droplets for high-sensitivity one-step detection of 17β-estradiol and other low-solubility molecules, with detection sensitivity improved by about 3 orders of magnitude than conventional systems.