Reliability of MRI-Derived Depth of Invasion of Oral Tongue Cancer
Reliability of MRI-Derived Depth of Invasion of Oral Tongue Cancer
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DOI：
10.1016/j.acra.2018.08.021
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发表时间：
2019-07-01
影响因子：
4.8
通讯作者：
Yamashita, Yasuyuki
中科院分区：
文献类型：
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作者：
Murakami, Ryuji;Shiraishi, Shinya;Yamashita, Yasuyuki
理论基础和目的：评估磁共振成像(MRI)得出的口腔舌癌侵袭深度(DOI)在评价者之间的可靠性，以及MRI与病理测量结果之间的一致性。材料和方法：机构审查委员会批准了这项回溯性研究。研究人群包括29例临床上接受手术治疗的T2N0口腔癌患者。常规预处理MRI在3T超导成像仪上进行。分别有23年和18年头颈部MRI经验的两名评分员为每个患者独立选择MRI序列，然后勾画肿瘤，然后使用三种方案测量MRI获得的DOI：轴向重建厚度(方法1)、轴向侵袭部分(方法2)和冠状侵袭部分(方法3)。然后，他们一致同意为每个患者在三种方法中选择最优的一种；将其命名为方法4。使用Bland-Altman曲线图、组内相关系数(ICCs)和配对样本检验。根据41个月的中位随访期，我们还探讨了MRI的DOI与淋巴结复发的关系。结果：方法2和方法4的评分者间信度良好(ICC值分别为0.829和0.807)。方法4(ICC值为0.611)的MRI测量结果与病理测量结果具有良好的相关性，但所有MRI测量结果均比病理测量结果大2-3 mm。MRI测得的DOI小于5 mm的患者无一例出现淋巴结复发。结论：MRI获得的DOI对术前分期有重要价值。应根据具体情况选择最佳测量方法。(C)2018年大学放射科医生协会。爱思唯尔公司出版，版权所有。
Rationale and Objective: To evaluate the inter-rater reliability of the magnetic resonance imaging (MRI)-derived depth of invasion (DOI) and the agreement between MRI and pathological measurements of oral tongue cancer. Materials and Methods: The institutional review board approved this retrospective study. The study population consisted of 29 patients with clinical T2N0 oral tongue cancer treated by surgery. Routine pretreatment MRI was performed on a 3T superconducting imager. Two raters with 23 and 18 years of head-and-neck MRI experience, respectively, independently chosen MRI sequences for each patient, then delineate the tumor, and then used three protocols to measure the MRI-derived DOI: the axial reconstructed thickness (method 1), the axial invasive portion (method 2), and the coronal invasive por-tion (method 3). Then they consensually selected the optimal among the three methods for each patient; it was designated method 4. The Bland-Altman plots, intraclass correlation coefficients (ICCs), and the paired samples test were used. According to the median follow-up of 41 months, the relationship between the MRI-derived DOI and nodal recurrence was also investigated. Results: The inter-rater reliability of methods 2 and 4 was excellent (ICC of 0.829 and 0.807, respec-tively). The correlation between MRI and pathological measurements was good for method 4 (ICC of 0.611), however, all measurements recorded on MRI were 2-3 mm larger than on pathology. No patients whose MRI-derived DOI was less than 5 mm suffered nodal recurrence. Conclusion: The MRI-derived DOI was valuable for the preoperative staging. The optimal measurement method should be selected on a case-by-case basis. (c) 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.