Sensitivity to pulse phase duration in cochlear implant listeners: Effects of stimulation mode
Sensitivity to pulse phase duration in cochlear implant listeners: Effects of stimulation mode
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DOI：
10.1121/1.4884773
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发表时间：
2014-08-01
影响因子：
2.4
通讯作者：
Kulkarni, Aditya M.
中科院分区：
文献类型：
--
作者：
Chatterjee, Monita;Kulkarni, Aditya M.
本研究的目的是研究在不同刺激模式(单极、双极、三极)下，人工耳蜗听者使用脉冲串刺激时的阈值电荷整合。这一结果部分证实和扩展了之前在动物模型中进行的研究的结果，该研究表明电荷整合依赖于刺激模式。初步的总体发现是，阈值-脉冲相位持续时间函数在单极模式下具有较陡的斜率，而在空间受限的模式下具有较浅的斜率。虽然在Cochlear Corporation(TM)设备的8名用户中得出的结果是明确的，但与6名参与其中的Advanced Bionics(TM)设备用户的结果却不太一致。不同的刺激方式很可能在同一神经元上激发不同的神经元群体和/或兴奋部位(例如，外周突起与中央轴突)。这些差异不仅可能影响电荷积分，还可能影响阈值以上水平和更多与语音相关的刺激的时间动力学。鉴于目前对聚焦刺激模式的兴趣，这些结果对人工耳蜗语音处理器的设计和用于将声幅映射到电刺激参数的协议具有指导意义。(C)2014年美国声学学会。
The objective of this study was to investigate charge-integration at threshold by cochlear implant listeners using pulse train stimuli in different stimulation modes (monopolar, bipolar, tripolar). The results partially confirmed and extended the findings of previous studies conducted in animal models showing that charge-integration depends on the stimulation mode. The primary overall finding was that threshold vs pulse phase duration functions had steeper slopes in monopolar mode and shallower slopes in more spatially restricted modes. While the result was clear-cut in eight users of the Cochlear Corporation (TM) device, the findings with the six user of the Advanced Bionics (TM) device who participated were less consistent. It is likely that different stimulation modes excite different neuronal populations and/or sites of excitation on the same neuron (e. g., peripheral process vs central axon). These differences may influence not only charge integration but possibly also temporal dynamics at suprathreshold levels and with more speech-relevant stimuli. Given the present interest in focused stimulation modes, these results have implications for cochlear implant speech processor design and protocols used to map acoustic amplitude to electric stimulation parameters. (C) 2014 Acoustical Society of America.