Sixth grade academic achievement among children conceived with IVF: a population-based study in Texas, USA.
Sixth grade academic achievement among children conceived with IVF: a population-based study in Texas, USA.
复制标题
通过体外受精受孕的儿童六年级的学业成绩：美国德克萨斯州的一项基于人群的研究。
DOI：
10.1007/s10815-021-02170-9
复制
发表时间：
2021
影响因子：
3.1
通讯作者：
Doody,KevinJ
中科院分区：
文献类型：
--
作者：
Luke,Barbara;Brown,MortonB;Ethen,MaryK;Canfield,MarkA;Watkins,Stephanie;Wantman,Ethan;Doody,KevinJ
目的比较体外受精（IVF）与自然受孕儿童六年级末阅读和数学成绩及三至六年级进展情况。方法：本研究是一项以人群为基础的回顾性队列研究，研究对象是在德克萨斯州接受三年级和六年级公立学校标准化阅读和数学测试的ivf怀孕的单胎和双胞胎儿童。结果三、六年级阅读成绩为6623人，三、六年级数学成绩为6374人。试管婴儿（IVF）和对照组独生子女阅读的平均（±SE）量表得分，三年级分别为1544.6±3.4和1527.7±1.9，六年级分别为1701.2±3.6和1681.0±2.0；三年级数学成绩分别为1564.4±3.7分和1548.9±2.1分，六年级数学成绩分别为1774.0±4.2分和1752.0±2.3分。在多变量模型中，单胎IVF患儿在阅读和数学方面的得分明显高于对照组，三年级和六年级的阅读平均分别高出17.7±4.0分和20.1±4.1分，三年级和六年级的数学平均分别高出17.8±4.4分和25.0±4.8分。结论8-9岁和10-12岁试管婴儿儿童在三年级和六年级阅读和数学方面的表现优于自然受孕儿童。
PurposeTo compare academic achievement in reading and mathematics at the end of sixth grade and progress from third to sixth grade by children conceived with in vitro fertilization (IVF) to those conceived naturally.MethodsThis was a retrospective population-based cohort study of IVF-conceived singleton and twin children who took the 3rd grade and 6th grade public school standardized reading and mathematics testing in Texas.ResultsThere were 6623 children with reading scores in both the third and sixth grades and 6374 children with mathematics scores in both the third and sixth grades. Mean (± SE) scaled test scores for IVF and control singleton children for reading were 1544.6 ± 3.4 and 1527.7 ± 1.9, respectively, in third grade and 1701.2 ± 3.6 and 1681.0 ± 2.0, respectively, in sixth grade; for mathematics, the scores were 1564.4 ± 3.7 and 1548.9 ± 2.1, respectively, in third grade and 1774.0 ± 4.2 and 1752.0 ± 2.3, respectively, in sixth grade. In multivariate models, singleton IVF children scored significantly higher than control children in reading and mathematics, averaging 17.7 ± 4.0 points and 20.1 ± 4.1 points higher, respectively, in reading in third and sixth grades and 17.8 ± 4.4 points and 25.0 ± 4.8 points higher, respectively, in mathematics in third and sixth grades.ConclusionsChildren conceived with IVF and aged 8–9 years and aged 10–12 years performed as well on third and sixth grade reading and mathematics assessments as their counterparts conceived naturally.