Maternal Trypanosoma cruzi infection, pregnancy outcome, morbidity, and mortality of congenitally infected and non-infected newborns in Bolivia
Maternal Trypanosoma cruzi infection, pregnancy outcome, morbidity, and mortality of congenitally infected and non-infected newborns in Bolivia
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DOI：
10.4269/ajtmh.2004.70.201
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发表时间：
2004-02-01
影响因子：
3.3
通讯作者：
Carlier, Y
中科院分区：
文献类型：
--
作者：
Torrico, F;Alonso-vega, C;Carlier, Y
这项工作比较了关于孕产妇慢性克氏锥虫感染后果的两项流行病学和临床调查的结果。它们于1992-1994年和1999-2001年在玻利维亚的同一产科诊所进行，玻利维亚是这种寄生虫感染高度流行的国家。在这两项调查中，5-6% 的受感染母亲发生了寄生虫母婴传播。当寄生虫没有母婴传播时，母亲慢性克氏锥虫感染对妊娠结局和新生儿健康没有影响。较旧的调查和最近的调查之间的比较突显出有症状病例的频率显着降低（从 54% 降至 45%），Apgar 评分
This work compares the results of two epidemiologic and clinical surveys on the consequences of maternal chronic Trypanosoma cruzi infection. They were conducted in 1992-1994 and 1999-2001 in the same maternity clinic in Bolivia, a country highly endemic for infection with this parasite. In both surveys, the materno-fetal transmission of parasites occurred in 5-6% of the infected mothers. Maternal chronic T. cruzi infection had no effect on pregnancy outcome and health of newborns when there was no materno-fetal transmission of parasites. Comparisons between the older and the more recent surveys highlighted significant reductions in frequencies of symptomatic cases (from 54% to 45%), Apgar scores