Associations between canine juvenile weight gain and coxofemoral joint laxity at 16 weeks of age.
Associations between canine juvenile weight gain and coxofemoral joint laxity at 16 weeks of age.
复制标题
幼年犬体重增加与 16 周龄时髋股关节松弛之间的关联。
DOI：
10.1111/j.1532-950x.2006.00139.x
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Markel,MarkD
中科院分区：
文献类型：
--
作者：
Lopez,MandiJ;Quinn,MargaretM;Markel,MarkD
目的：评价犬在6-15周龄体重增加与16周龄被动髋股关节松弛的关系。研究设计-纵向队列研究。动物-全或半同胞猎犬(n=56)。计算每周(每周)和研究(总体)的个体平均日增重(ADG)。在16周时测定每个CFJ的PennHIP分心指数(DI)。混合效应线性模型评估DI(最高和平均)与15周体重和ADGs(实际或归一化)的相关性。左侧和右侧DIS与学生配对t检验进行比较。重要的是设定了ATP<；0.05。结果平均(±SD)16周DI评分为0.6 7±0.16，15周体重为12.5±1.8 kg。在动物体内，左、右DIS差异无统计学意义。在DI和任何评估的体重增加之间没有显著的关联。在一个统计模型中，标准化的14周ADG和DI之间存在负相关的趋势。结论-在具有中到重度CFJ关节松弛的同种犬种中，6-15周龄的体重增加与16周龄的PennHIP DI无关。临床相关性--根据我们的结果，根据PennHIP DI的测量，6-15周龄的随意喂养似乎对16周龄的关节松弛没有不利影响。
Objective—Evaluation of the relationship between canine weight gain from 6 to 15 weeks of age and passive coxofemoral joint (CFJ) laxity at 16 weeks of age.Study Design—Longitudinal cohort study.Animals—Full‐ or half‐sibling hounds (n=56).Methods—Hounds were weighed weekly from 6 to 15 weeks of age. Individual average daily gain (ADG) was calculated for each week (weekly) and for the study (overall). PennHIP distraction index (DI) was determined for each CFJ at 16 weeks. Mixed effects linear models were evaluated for associations of DI (highest and mean) with 15‐week weight and ADGs (actual or normalized). Left and right DIs were compared with a Student's paired t‐test. Significance was set atP<.05. Trends were considered atP<.10.Results—Mean (±SD) 16‐week DI score and 15‐week weight was 0.67±0.16 and 12.5±1.8 kg, respectively. Within animal left and right DIs were not significantly different. There were no significant associations between DI and any of the weight gains evaluated. There was a trend for a negative relationship between normalized 14‐week ADG and DI in one statistical model.Conclusions—Weight gain from 6 to 15 weeks of age was unrelated to 16‐week PennHIP DI in a homogenous canine population with moderate‐to‐severe CFJ joint laxity.Clinical Relevance—Based on our results, ad libitum feeding between 6 and 15 weeks of age does not appear to have an adverse impact on joint laxity at 16 weeks of age as measured by the PennHIP DI.